Lenbelintide
Lenbelintide is a dual amylin/calcitonin receptor agonist. Lenbelintide can be studied in research on obesity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2793341-99-6
- Fòrmula: C202H319N55O63S2
- Peso molecular:4590.15
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Amylin receptors (AMYRs) are G protein-coupled receptors (GPCRs), which respond to the peptide hormones amylin and calcitonin. Amylin is originally discovered as the main constituent of pancreatic islet amyloid deposits in type 2 diabetics and in diabetic cats, amylin is also a physiologically relevant circulating peptide hormone. Amylin receptors are heterodimers comprising the calcitonin receptor, which is a G protein–coupled receptor, and one of three receptor-modifying proteins. An impediment to functional studies is that it is difficult to separate amylin receptor phenotypes from calcitonin receptor phenotypes. Amylin receptors are targets for treating obesity and metabolic disorders.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2793341-99-6
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Peso molecular 4590.15
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Fòrmula C202H319N55O63S2
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Sequence
{Lys-(γGlu-γGlu-C18 diacid)}-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-{(α-Me-Phe)}-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Glu-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (disulfide bridge:Cys2-Cys7)
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Sequence Shortening
{Lys-(γGlu-γGlu-C18 diacid)}-CNTATCATQRLANFLRHSSNN-{(α-Me-Phe)}-GPILPPTEVGSNTY-NH2 (disulfide bridge:Cys2-Cys7)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)