Meglutol-d3
Based on 1 Customer Validation
Meglutol-d3 is the deuterium labeled Meglutol. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
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- Pureza : 98.04%
- No. CAS: 59060-36-5
- Fòrmula: C6H7D3O5
- Peso molecular:165.16
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 59060-36-5
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Unlabeled CAS 503-49-1
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Appearance Solid
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Peso molecular 165.16
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Fòrmula C6H7D3O5
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Color White to off-white
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SMILES
OC(CC(C([2H])([2H])[2H])(O)CC(O)=O)=O
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Synonyms
Dicrotalic acid-d3; 3-Hydroxy-3-methylglutaric acid-d3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
Methanol : 100 mg/mL (605.47 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 6.0547 mL | 30.2737 mL | 60.5473 mL | 151.3684 mL |
| 5 mM | 1.2109 mL | 6.0547 mL | 12.1095 mL | 30.2737 mL | |
| 10 mM | 0.6055 mL | 3.0274 mL | 6.0547 mL | 15.1368 mL | |
| 15 mM | 0.4036 mL | 2.0182 mL | 4.0365 mL | 10.0912 mL | |
| 20 mM | 0.3027 mL | 1.5137 mL | 3.0274 mL | 7.5684 mL | |
| 25 mM | 0.2422 mL | 1.2109 mL | 2.4219 mL | 6.0547 mL | |
| 30 mM | 0.2018 mL | 1.0091 mL | 2.0182 mL | 5.0456 mL | |
| 40 mM | 0.1514 mL | 0.7568 mL | 1.5137 mL | 3.7842 mL | |
| 50 mM | 0.1211 mL | 0.6055 mL | 1.2109 mL | 3.0274 mL | |
| 60 mM | 0.1009 mL | 0.5046 mL | 1.0091 mL | 2.5228 mL | |
| 80 mM | 0.0757 mL | 0.3784 mL | 0.7568 mL | 1.8921 mL | |
| 100 mM | 0.0605 mL | 0.3027 mL | 0.6055 mL | 1.5137 mL |
Meglutol-d3 Related Classifications
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