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Referencia número: HY-125088

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Oleoylestrone

Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure.

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No. CAS: 180003-17-2
Fòrmula: C₃₆H₅₄O₃
Peso molecular:534.81

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

Oleoylestrone Chemical Structure

No. CAS: 180003-17-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
- In Vitro
- Ensayo clínico
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Sf9	EC₅₀	~ 10 nM Compound: 1-oleoyl (table 1)	Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells	[PMID: 15857137]

In Vitro

Oleoylestrone is an adipose tissue-derived hormonal signal that elicits the decrease of body fat stores. This is accomplished by decreasing white adipose tissue mass through apoptosis and massive loss of lipid, accompanied by a decrease in food intake and the maintenance of energy expenditure^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ensayo clínico

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

No. CAS 180003-17-2
Peso molecular 534.81
Fòrmula C₃₆H₅₄O₃
SMILES

C[C@]12[C@]([H])([C@@]3(CCC4=C([C@]3(CC2)[H])C=CC(OC(CCCCCCC/C=C\CCCCCCCC)=O)=C4)[H])CCC1=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. del Mar Grasa M, et al. Corticosterone inhibits the lipid-mobilizing effects of oleoyl-estrone in adrenalectomized rats. Endocrinology. 2007 Aug;148(8):4056-63. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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