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Ozureprubart

(Synonyms: JYB-1904; RPT904)
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Based on 1 Customer Validation

Ozureprubart (JYB-1904; RPT904) is an anti-IgE humanized monoclonal antibody. Ozureprubart blocks the binding of IgE to FcαRI and dissociates bound IgE by binding free immunoglobulin E (IgE), while reducing receptor-bound IgE and FcαRI on basophils. The antibody carries a YTE mutation in the Fc fragment to extend serum half-life and has modifications that increase IgE binding affinity, improve stability, and reduce immunogenicity potential, and it can be used for research on allergic asthma, chronic spontaneous urticaria, and allergic inflammatory diseases.

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  • Pureza : 98.624%
  • No. CAS: 2823332-50-7
  • Peso molecular:146.518 kDa
  • Almacenamiento:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ozureprubart
  • Experimental Validation Results for Ozureprubart
  • Ozureprubart Chemical Structure
    Ozureprubart Chemical Structure
No. CAS: 2823332-50-7
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Ozureprubart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized IgE Protein, Human (HEK293, His, HY-P73907) can bind Ozureprubart. The EC50 for this effect is 9.58 ng/mL.

  • Ozureprubart Chemical Structure
    1/16
  • Ozureprubart
  • Immobilized IgE Protein, Human (HEK293, His, HY-P73907) can bind Ozureprubart. The EC50 for this effect is 9.58 ng/mL.
  • IgG1-kappa