Q8
Q8, an effective antiangiogenic drug, is a CysLt1 antagonist (IC50 of 4.9 μM). Q8 is sufficient to reduce cellular levels of NF-κB and calpain-2 and secreted levels of the proangiogenic proteins intercellular adhesion molecule-1, vascular cell adhesion protein-1, and VEGF.
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- No. CAS: 1541762-55-3
- Fòrmula: C17H14ClNO2
- Peso molecular:299.75
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Ver todos los productos específicos de isoformas Leukotriene Receptor
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Actividad biológica
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 1541762-55-3
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Peso molecular 299.75
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Fòrmula C17H14ClNO2
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SMILES
OC1=CC=C(O)C=C1/C=C/C2=NC3=CC=CC=C3C=C2.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Q8 Related Classifications
HY-127113 Related Classifications
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