QMT-CBT
QMT-CBT is a near-infrared aggregation-induced luminescent photon. After activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction to form a cyclic dimer QMT-Dimer (the first aggregate) and assembles into nanoparticles (the second aggregate), turning the AIE signal "on" to enhance imaging of Alzheimer's disease (AD).
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- Fòrmula: C94H89N19O12S4
- Peso molecular:1805.09
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
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Peso molecular 1805.09
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Fòrmula C94H89N19O12S4
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Sequence
Ac-Trp-Glu-His-Asp-{Cys(StBu)}-{Pra(QMT)}-CBT
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Sequence Shortening
Ac-WEHD-{Cys(StBu)-{Pra(QMT)}-CBT
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)