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RC148

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Based on 1 Customer Validation

RC148 is a humanized IgG1 bispecific antibody targeting VEGF and PD-1. RC148 blocks PD-1-PD-L1 and VEGF-VEGFR interactions, triggers VEGF-dependent enhanced PD-1 binding, enables VEGF crosslinking, and inhibits PD-1-mediated immunosuppression. RC148 can be used for the research of metastatic gastric/gastroesophageal junction adenocarcinoma, non-small cell lung cancer, and metastatic breast cancer.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.72%
  • Peso molecular:167.34 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for RC148
  • Experimental Validation Results for RC148
  • Experimental Validation Results for RC148
  • RC148 Chemical Structure
    RC148 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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RC148 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human PD1 Protein, His Tag can bind RC148. The EC50 for this effect is 148.6 ng/mL.

  • 1/16

    Immobilized Human VEGF165 Protein, hFc Tag can bind RC148. The EC50 for this effect is 106 ng/mL.

  • RC148 Chemical Structure
    1/16
  • RC148
  • Immobilized Human PD1 Protein, His Tag can bind RC148. The EC50 for this effect is 148.6 ng/mL.
  • Immobilized Human VEGF165 Protein, hFc Tag can bind RC148. The EC50 for this effect is 106 ng/mL.