RY 024
RY 024 is an active compound.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 173990-15-3
- Fòrmula: C19H19N3O3
- Peso molecular:337.37
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | EC50 |
324.4 μM
Compound: RY-024
|
Activity at alpha-4-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-4-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
51.7 μM
Compound: RY-024
|
Activity at alpha-6-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-6-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
74.4 μM
Compound: RY-024
|
Activity at GABAA alpha-1-beta-3-gamma-2 receptor expressed in Xenopus oocytes assessed as inhibition of GABA-induced current by voltage clamp assay
Activity at GABAA alpha-1-beta-3-gamma-2 receptor expressed in Xenopus oocytes assessed as inhibition of GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
9.8 μM
Compound: RY-024
|
Activity at alpha-5-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-5-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
| Oocyte | EC50 |
95.5 μM
Compound: RY-024
|
Activity at alpha-2-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
Activity at alpha-2-beta-3-gamma-2 GABAA receptor expressed in Xenopus oocytes assessed as inhibition in GABA-induced current by voltage clamp assay
|
[PMID: 18537233] |
Chemical Information
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No. CAS 173990-15-3
-
Peso molecular 337.37
-
Fòrmula C19H19N3O3
-
SMILES
O=C(OC(C)(C)C)C1=C(CN2C)N(C3=CC=C(C=C3C2=O)C#C)C=N1
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Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)