2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

Referencia número: HY-118656
No. CAS: 31508-71-1
Target:  

Cannabinoid Receptor

Áreas de investigación:  

Neurological Disease

Cannabicitran is a cannabinoid. Cannabicitran can decrease intraocular pressure in rabbits .
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Referencia número: HY-101606
No. CAS: 62992-61-4
Synonyms: Eterylate; Etherylate
Áreas de investigación:  

Cardiovascular Disease Endocrinology

Etersalate inhibits platelet function and decreases thromboxane A2 (TXA2) levels.
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Referencia número: HY-104037A
No. CAS: 2055538-47-9
Synonyms: LYC-55716 sodium
Target:  

ROR

Áreas de investigación:  

Cancer

Cintirorgon sodium is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon sodium (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved survival .
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Referencia número: HY-159518
No. CAS: 2959444-40-5
Áreas de investigación:  

Cancer

ROS inducer 4 (compound TE3) is a mitochondrial inhibitor. ROS inducer 4 causes a series of mitochondria-related physiological changes in tumors, such as mitochondrial fragmentation, explosive generation and accumulation of ROS, decreased mitochondrial membrane potential, decreased ATP content, and activation of ROS-mediated apoptotic signaling in mitochondria .
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Referencia número: HY-107992
No. CAS: 79770-24-4
Áreas de investigación:  

Infection Endocrinology

Iotrolan is a non-ionic contrast agent. Iotrolan induces Apoptosis. Iotrolan decreases glomerular filtration rate and renal perfusate flow, increases urine flow, and does not significantly decrease fractional sodium reabsorption. Iotrolan can be used in studies of COVID-19 and contrast-induced nephrotoxicity .
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Referencia número: HY-158333
No. CAS: 88579-39-9
Target:  

Mucin

Áreas de investigación:  

Others

Tasuldine is a mucolytic agent, which decreases the sialomucin content of mucus, improves mucociliary and cough clearance .
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Referencia número: HY-110216
No. CAS: 827001-82-1
Pureza:  95%
Target:  

CRAC Channel

Áreas de investigación:  

Inflammation/Immunology

5J-4 is a potent CRAC inhibitor. 5J-4 decreases the numbers of infiltrated mononuclear cell into the CNS, and significantly decreases the population of infiltrated CD4+ population. 5J-4 reduces the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in mouse model of inflammation .
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Referencia número: HY-120067
No. CAS: 183012-13-7
Target:  

Cytochrome P450

Áreas de investigación:  

Endocrinology

YM116 is an orally active and competitive CYP17A1 (17,20-lyase) inhibitor (Ki: 0.38 nM). YM116 reduces the synthesis of adrenal androgens by preferentially inhibiting C17-20 lyase activity. YM116 decreases the serum testosterone concentration, reduces dehydroepiandrosterone sulfate levels and decreases prostatic weights .
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Referencia número: HY-122007
No. CAS: 1202764-63-3
Target:  

NF-κB

Áreas de investigación:  

Cancer

AM-0561 is a NIK inhibitor (Ki: 0.3 nM). AM-0561 decreases p52 levels .
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Referencia número: HY-114929
No. CAS: 104741-27-7
Target:  

Glutaminase

Áreas de investigación:  

Neurological Disease

THDP17 is an orally active glutaminase inhibitor. THDP17 decreases ammonia production through glutaminase inhibition .
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Referencia número: HY-168884
No. CAS: 2713387-11-0
Target:  

mTOR

Áreas de investigación:  

Metabolic Disease

AV457 is a potent and selective mTOR inhibitor with an IC50 value of 0.54 µM. AV457 inhibits cyst growth in polycystic kidney disease (PKD) organoids. AV457 decreases the protein expression of P-s6, P-p70s6 and don’t decreases the protein expression of P-AKT .
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Referencia número: HY-130434
No. CAS: 51350-61-9
Target:  

Endogenous Metabolite

Áreas de investigación:  

Cancer

12-SAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 12-SAHSA decreases in the human serum of breast cancer .
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Referencia número: HY-124560
No. CAS: 96609-16-4
Target:  

LDLR

Áreas de investigación:  

Metabolic Disease

Lifibrol is a potent and oral activity hypolipidemic agent. Lifibrol decreases the plasma total cholesterol. Lifibrol has the potential for the research of hypercholesterolemia .
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Referencia número: HY-114189A
No. CAS: 179246-08-3
Synonyms: UNC10225170 hydrochloride
Target:  

MEK

Áreas de investigación:  

Cancer

GW284543 (UNC10225170) hydrochloride is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein .
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Referencia número: HY-160436
No. CAS: 364039-58-7
Target:  

TNF Receptor

Áreas de investigación:  

Inflammation/Immunology

TNF-α-IN-15 is a TNF-α inhibitor. TNF-α-IN-15 can decrease the TNF-α blood levels .
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Referencia número: HY-P5069
No. CAS: 97451-40-6
Target:  

Endogenous Metabolite

Áreas de investigación:  

Metabolic Disease

Glutathione diethyl ester is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
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Referencia número: HY-126482
No. CAS: 1610878-54-0
Pureza:  99.79%
Target:  

Telomerase

Áreas de investigación:  

Cancer

Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC50 of 0.89 µM. Anti-cancer activity .
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Referencia número: HY-17556B
No. CAS: 1097832-14-8
Synonyms: Leucovorin calcium hydrate
Folinic acid (Leucovorin) calcium hydrate is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease Methotrexate-induced toxicity .
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Referencia número: HY-N1616
No. CAS: 120211-98-5
1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis .
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Referencia número: HY-105259
No. CAS: 114037-60-4
Target:  

Renin

Áreas de investigación:  

Cardiovascular Disease

SR 43845 is a renin inhibitor. SR 43845 decreases blood pressure and inhibits plasma renin activity. SR 43845 can be used for hypertension research .
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