TOR-G4
TOR-G4 is a Fluorescent probe that binds to G-quadruplex (G4) nucleic acid structures. TOR-G4 exhibits a unique fluorescence lifetime when bound to G4 compared to other structures, enabling sensitive discrimination between G4-bound and non-G4-bound states. TOR-G4 mainly colocalizes with RNA in the cytoplasm and nucleolus. TOR-G4 can be used to investigate the roles of RNA G4 in cells. TOR-G4 shows cytotoxicity against osteosarcoma cells.
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- No. CAS: 3030070-69-7
- Fòrmula: C30H30IN3OS
- Peso molecular:607.55
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
TOR-G4 (6 h) exhibits cytotoxicity toward U2OS cells with a GI50 of 143 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3030070-69-7
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Peso molecular 607.55
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Fòrmula C30H30IN3OS
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SMILES
CN(C)C(C=C1)=CC=C1/C=C/C2=C/C(C3=CC=CC=C3N2C)=C\C4=[N+](C)C5=C(C=CC(OC)=C5)S4.[I-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)