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Referencia número: HY-116469

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ZP7

ZP7 (compound 7c) is a potent anti-HIV-1 agent with an EC₅₀ of 36.4nM. ZP7 can be utilized in HIV-1 research.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1188890-60-9
Fòrmula: C₁₅H₉Br₂ClN₄OS₂
Peso molecular:520.65

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

ZP7 Chemical Structure

No. CAS: 1188890-60-9

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Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
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Actividad biológica

Descripciòn

ZP7 (compound 7c) is a potent anti-HIV-1 agent with an EC₅₀ of 36.4nM. ZP7 can be utilized in HIV-1 research^[1].

Ver todos los productos específicos de isoformas HIV :

Cellular Effect

Cell Line	Type	Value	Description	References
MT4	CC₅₀	>240.08 μM Compound: 7c	Cytotoxicity against human MT4 cells after 5 days by MTT assay Cytotoxicity against human MT4 cells after 5 days by MTT assay	[PMID: 19620009]
MT4	EC₅₀	>240.08 μM Compound: 7c	Antiviral activity against HIV2 ROD infected in human MT4 cells after 5 days by MTT assay Antiviral activity against HIV2 ROD infected in human MT4 cells after 5 days by MTT assay	[PMID: 19620009]
MT4	EC₅₀	0.0364 μM Compound: 7c	Antiviral activity against HIV1 3B infected in human MT4 cells after 5 days by MTT assay Antiviral activity against HIV1 3B infected in human MT4 cells after 5 days by MTT assay	[PMID: 19620009]
MT4	EC₅₀	36.4 μM Compound: ZP7	Antiviral activity against HIV-1 3B infected human MT4 cells assessed as inhibition in viral syncytium formation by MTT assay Antiviral activity against HIV-1 3B infected human MT4 cells assessed as inhibition in viral syncytium formation by MTT assay	[PMID: 22883027]

Chemical Information

No. CAS 1188890-60-9
Peso molecular 520.65
Fòrmula C₁₅H₉Br₂ClN₄OS₂
SMILES

O=C(CSC1=C(C2=C(Br)C=C(Br)C=C2)N=NS1)NC3=CC=CN=C3Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Zhan P, et al. Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies. Bioorg Med Chem. 2009 Aug 15;17(16):5920-7. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Actividad biológica
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ZP7

Ver todos los productos específicos de isoformas HIV

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

ZP7 Related Classifications

HY-116469 Related Classifications