CASR - calcium sensing receptor Gene
Also Known as PCAR1
Species: Sus scrofa
Gene Type: protein coding
Gene ID: 100520980
About CASR
Primary_assembly 13: 138,280,364-138,364,252 reverse strand.Sscrofa11.1:CM000824.5
This gene has 2 transcripts (splice variants), 203 orthologues and 12 paralogues. Biased expression in kidney (RPKM 4.2), ovary (RPKM 1.4) and 2 other tissues.
CASR Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001278748.1 | NP_001265677.1 | extracellular calcium-sensing receptor precursor |
CASR Protein Structure
PBP1_CaSR
PBP1_CaSR: cd06364 (32 - 529)
NCD3G
NCD3G: pfam07562 (547 - 600)
7tmC_CaSR
7tmC_CaSR: cd15282 (620 - 645)
7tmC_CaSR
7tmC_CaSR: cd15282 (620 - 871)
7tmC_CaSR
7tmC_CaSR: cd15282 (657 - 678)
7tmC_CaSR
7tmC_CaSR: cd15282 (687 - 711)
7tmC_CaSR
7tmC_CaSR: cd15282 (735 - 751)
7tmC_CaSR
7tmC_CaSR: cd15282 (778 - 804)
7tmC_CaSR
7tmC_CaSR: cd15282 (812 - 835)
7tmC_CaSR
7tmC_CaSR: cd15282 (840 - 865)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1089 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
extracellular calcium-sensing receptor |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(8)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-70037 | Cinacalcet | Agonist | 99.93% | Yes |
| HY-70037A | Cinacalcet hydrochloride | Agonist | 99.98% | Yes |
| HY-P1955A | Etelcalcetide hydrochloride | Activator | 99.80% | Unkown |
| HY-17397 | Strontium Ranelate | Activator | 99.30% | Unkown |
| HY-17613 | Evocalcet | Activator | 99.28% | Unkown |
| HY-109106A | Upacicalcet sodium | Agonist | 99.91% | Unkown |
| HY-P1955 | Etelcalcetide | Activator | / | Unkown |
| HY-109106 | Upacicalcet | Agonist | / | Unkown |
Clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-10007 | NPS-2143 | Antagonist | 99.94% | Phase 2 |
| HY-10167A | Tecalcet Hydrochloride | Modulator | 99.43% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(45)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-139201A | Poly-D-lysine hydrobromide (MW 70000-150000) | Agonist | 99.86% | Unkown |
| HY-139201 | Poly-D-lysine hydrobromide (MW 30000-70000) | Agonist | / | Unkown |
| HY-112171 | γ-L-Glutamyl-L-alanine | Modulator | 98.0% | Unkown |
| HY-12557 | γ-Glutamylvaline | Agonist | 99.94% | Unkown |
| HY-10171 | NPS-2143 hydrochloride | Antagonist | 99.98% | Unkown |
| HY-103320A | Calhex 231 hydrochloride | Inhibitor | 99.81% | Unkown |
| HY-N0546 | Ligustroflavone | Antagonist | 99.90% | Unkown |
| HY-139201B | Poly-D-lysine hydrobromide (MW 84000) | Agonist | / | Unkown |
| HY-11095 | NPS 2390 | Inhibitor | 99.90% | Unkown |
| HY-14401 | Encaleret | Antagonist | 99.88% | Unkown |
| HY-122819 | Calindol hydrochloride | Agonist | 99.64% | Unkown |
| HY-121584 | Lycoperodine-1 | Agonist | 99.82% | Unkown |
| HY-139201D | Poly-D-lysine hydrobromide (MW 4000-15000) | / | Unkown | |
| HY-W843885 | H-Glu-Thr-OH | Activator | 98.63% | Unkown |
| HY-P4376A | Gamma-Glu-Abu TFA | Agonist | 96.83% | Unkown |
| HY-103320B | (1R,2R)-Calhex 231 hydrochloride | Control | 98.45% | Unkown |
| HY-117851 | AC-265347 | Agonist | 99.97% | Unkown |
| HY-112171R | γ-L-Glutamyl-L-alanine (Standard) | Modulator | 99.29% | Unkown |
| HY-50713 | Calcium-Sensing receptor antagonist I | Antagonist | 98.95% | Unkown |
| HY-139201E | Poly-D-lysine hydrobromide (MW 150000-300000) | Agonist | / | Unkown |
| HY-107773 | GSK3004774 | Agonist | 99.09% | Unkown |
| HY-139201H | Poly-D-lysine hydrobromide (MW ≥300000) | Activator | / | Unkown |
| HY-15105 | SB-423562 | Antagonist | 99.66% | Unkown |
| HY-15104 | Ronacaleret hydrochloride | Antagonist | 99.81% | Unkown |
| HY-70037AS | Cinacalcet-d3 hydrochloride | Agonist | 97.63% | Unkown |
| HY-W777503 | Calindol hydrochloride-13C,D2 | / | Unkown | |
| HY-P11832 | CaSR agonist peptide-1 | Agonist | / | Unkown |
| HY-153258 | CaSR antagonist-1 | Antagonist | / | Unkown |
| HY-103320 | Calhex 231 | Antagonist | / | Unkown |
| HY-15106 | SB-423557 | Antagonist | / | Unkown |
| HY-14752 | Ronacaleret | Antagonist | / | Unkown |
| HY-10167 | Tecalcet | Modulator | / | Unkown |
| HY-179475 | KP-2067 | Agonist | / | Unkown |
| HY-177303 | AXT-914 | Inhibitor | 98.83% | Unkown |
| HY-P11668 | Gosicalcetide | Agonist | / | Unkown |
| HY-109106B | (Rac)-Upacicalcet | 95.0% | Unkown | |
| HY-139201C | Poly-D-lysine hydrobromide (MW 1000-5000) | Activator | / | Unkown |
| HY-70037S | Cinacalcet-d3 | Agonist | / | Unkown |
| HY-P4376 | Gamma-Glu-Abu | Agonist | / | Unkown |
| HY-14401B | Encaleret sodium | Antagonist | / | Unkown |
| HY-161113 | Z8554052021 | Activator | / | Unkown |
| HY-17613S | Evocalcet-d4 | Activator | / | Unkown |
| HY-W653978 | Cinacalcet-d4 hydrochloride | Agonist | / | Unkown |
| HY-182543 | NPS-467 | Activator | / | Unkown |
| HY-171446 | TAK-075 | Antagonist | / | Unkown |
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