2. Gene
  3. MFSD10 - major facilitator superfamily domain containing 10 Gene

MFSD10 - major facilitator superfamily domain containing 10 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TETRAN; TETTRAN

Gene ID: 10227 | Gene type: protein coding

About MFSD10

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:2,930,567-2,934,825 (from NCBI)

This gene has 11 transcripts (splice variants), 571 orthologues and 6 paralogues. Ubiquitous expression in bone marrow (RPKM 36.8), spleen (RPKM 13.5) and 24 other tissues.

Summary

This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein likely functions in efflux of organic anions, including the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

MFSD10 Products(4)

mRNA Protein Name
NM_001120.5 NP_001111.3 major facilitator superfamily domain-containing protein 10 isoform a
NM_001146069.2 NP_001139541.1 major facilitator superfamily domain-containing protein 10 isoform a
NM_001363679.2 NP_001350608.1 major facilitator superfamily domain-containing protein 10 isoform b
NM_001410703.1 NP_001397632.1 major facilitator superfamily domain-containing protein 10 isoform c

MFSD10 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (28 - 412)

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  • 455 a.a.
Protein Preferred Names Protein Names

major facilitator superfamily domain-containing protein 10

tetracycline transporter-like protein

Related Diseases

Diseases Alias
Mahvash Disease

Gcgr-Related Hyperglucagonemia

MVAH

Alpha-Cell Hyperplasia With Glucagonemia

Nesidioblastosis, Alpha Cell Hyperplasia, Microglucagonoma, And Nonfunctioning Islet Cell Tumor

Nesidioblastosis Alpha Cell Hyperplasia Microglucagonoma And Nonfunctioning Islet Cell Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08388 MFSD10 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MFSD10 VGNC VGNC:63475
Canis familiaris MFSD10 VGNC VGNC:43196
Rattus norvegicus MFSD10 RGD RGD:1311900
Bos taurus MFSD10 VGNC VGNC:31432
Macaca mulatta MFSD10 VGNC VGNC:100247
Mus musculus MFSD10 MGD MGI:1915544