2. Gene
  3. POLR3G - RNA polymerase III subunit G Gene

POLR3G - RNA polymerase III subunit G Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C31; RPC7; RPC32

Gene ID: 10622 | Gene type: protein coding

About POLR3G

Cytogenetic location: 5q14.3 Genomic coordinates (GRCh38): 5:90,473,929-90,514,557 (from NCBI)

This gene has 7 transcripts (splice variants) and 19 orthologues. Broad expression in testis (RPKM 1.8), esophagus (RPKM 1.0) and 24 other tissues.

Summary

Enables chromatin binding activity. Involved in positive regulation of innate immune response; positive regulation of interferon-beta production; and transcription by RNA polymerase III. Acts upstream of or within cell population proliferation. Located in cytosol and nuclear body. Part of RNA polymerase III complex. [provided by Alliance of Genome Resources, Apr 2022]

POLR3G Products(5)

mRNA Protein Name
NM_001370351.1 NP_001357280.1 DNA-directed RNA polymerase III subunit RPC7 isoform 1
NM_001370352.1 NP_001357281.1 DNA-directed RNA polymerase III subunit RPC7 isoform 2
NM_001370353.1 NP_001357282.1 DNA-directed RNA polymerase III subunit RPC7 isoform 2
NM_001370354.1 NP_001357283.1 DNA-directed RNA polymerase III subunit RPC7 isoform 1
NM_006467.3 NP_006458.2 DNA-directed RNA polymerase III subunit RPC7 isoform 1

POLR3G Protein Structure

RNA_pol_3_Rpc31

RNA_pol_3_Rpc31: DNA-directed RNA polymerase III subunit Rpc31 (1 - 223)

  • 0
  • 100
  • 200
  • 223 a.a.
Protein Preferred Names Protein Names

DNA-directed RNA polymerase III subunit RPC7

DNA-directed RNA polymerase III 32 kDa polypeptide

Related Diseases

Diseases Alias
Cerebellofaciodental Syndrome

Cerebellar-Facial-Dental Syndrome

CFDS
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10860 POLR3G Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus POLR3G RGD RGD:1593792
Canis familiaris POLR3G VGNC VGNC:44805
Bos taurus POLR3G VGNC VGNC:33151
Macaca mulatta POLR3G VGNC VGNC:84480
Mus musculus POLR3G MGD MGI:1914736