U2af1 - U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 Gene

Also Known as 2010107D16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 108121

Summary

Enables RS domain binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in nuclear speck. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and skeleton. Orthologous to human U2AF1 (U2 small nuclear RNA auxiliary factor 1). [provided by Alliance of Genome Resources, Apr 2022]

U2af1 Products (3)

mRNA Protein Name
NM_001163769.1 NP_001157241.1 splicing factor U2AF 35 kDa subunit isoform 2
NM_001357907.1 NP_001344836.1 splicing factor U2AF 35 kDa subunit isoform 3
NM_024187.4 NP_077149.2 splicing factor U2AF 35 kDa subunit isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RS domain binding IPI
IPI: Inferred from physical interaction
15798186 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18758164 MGI
Cellular Component GO Annotation Evidence References Source
located in nuclear speck IDA
IDA: Inferred from direct assay
18758164 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing factor U2AF 35 kDa subunit

  • U2 auxiliary factor 35 kDa subunit

  • U2 snRNP auxiliary factor small subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153736 NSC 194308 99.86% Unkown
HY-178155A AP232 dihydrochloride Inhibitor / Unkown
HY-178155 AP232 Inhibitor / Unkown
HY-139499 Sudemycin D6 Modulator / Unkown
HY-RS15313 U2AF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18687 U2af1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25173 U2af1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens U2af1 NCBI NCBI:7307