Sri - sorcin Gene

Also Known as Sor; 2210417O06Rik; 2900070H08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109552

Summary

Enables DNA-binding transcription factor binding activity. Involved in several processes, including cytoplasmic sequestering of transcription factor; negative regulation of cardiac muscle contraction; and positive regulation of transport. Acts upstream of or within calcium ion transport. Located in Z disc; plasma membrane; and vesicle. Orthologous to human SRI (sorcin). [provided by Alliance of Genome Resources, Apr 2022]

Sri Products (2)

mRNA Protein Name
NM_001080974.2 NP_001074443.1 sorcin isoform 1
NM_025618.3 NP_079894.2 sorcin isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
22338092 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14644162 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium ion transport IPI
IPI: Inferred from physical interaction
16204356 MGI
involved in cytoplasmic sequestering of transcription factor IMP
IMP: Inferred from mutant phenotype
22338092 MGI
involved in negative regulation of cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
22326846 MGI
involved in negative regulation of transcription regulatory region DNA binding IMP
IMP: Inferred from mutant phenotype
22338092 MGI
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
22338092 MGI
involved in positive regulation of release of sequestered calcium ion into cytosol IMP
IMP: Inferred from mutant phenotype
22338092 MGI
Cellular Component GO Annotation Evidence References Source
located in Z disc IDA
IDA: Inferred from direct assay
12754254 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
14644162 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
14644162 MGI
located in vesicle IDA
IDA: Inferred from direct assay
12925238 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorcin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (31)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100347 SRI-011381 Agonist 99.58% Unkown
HY-19956 GI254023X Inhibitor 99.67% Unkown
HY-100347A SRI-011381 hydrochloride Agonist 99.94% Unkown
HY-150090 SRI-41315 Activator 99.68% Unkown
HY-141623 SRI-37330 hydrochloride Inhibitor 99.72% Unkown
HY-142114 SRI-37330 Inhibitor 99.16% Unkown
HY-148853 SRI-42127 Inhibitor 99.80% Unkown
HY-114363A SRI 31215 TFA Inhibitor 98.35% Unkown
HY-123600 SRI-29329 Inhibitor 99.14% Unkown
HY-150089 SRI-37240 Modulator 98.29% Unkown
HY-117002 SRI 37892 Inhibitor 99.28% Unkown
HY-147251 SRI 6409-94 99.25% Unkown
HY-160783 SRI-43265 Inhibitor 98.70% Unkown
HY-178061 APS03118 Inhibitor / Unkown
HY-117902 SRI-31142 99.89% Unkown
HY-75368 SRI-31255 Inhibitor 99.88% Unkown
HY-112580 SRI-31040 / Unkown
HY-114363 SRI 31215 Inhibitor / Unkown
HY-126158 SRI-29574 / Unkown
HY-165543 SRI-29132 Inhibitor / Unkown
HY-175661 SRI-22136 / Unkown
HY-182446 SRI-22818 Activator / Unkown
HY-182611 SRI-31277 / Unkown
HY-182612 SRI-35241 Antagonist / Unkown
HY-RS13767 SRI Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100347S SRI-011381-d5 Agonist / Unkown
HY-175534 SRI-45949 Modulator / Unkown
HY-175535 SRI-32743 / Unkown
HY-N9533 16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid / Unkown
HY-RS17159 Sri Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23609 Sri Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sri NCBI NCBI:6717
Macaca fascicularis Sri NCBI NCBI:102138728
Macaca mulatta Sri NCBI NCBI:705215