SRI 6409-94
Based on 1 Customer Validation
SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. SRI 6409-94 serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity.
For research use only. We do not sell to patients.
- Purity: 99.25%
- CAS No.: 127697-58-9
- Formula: C24H29NO3
- Molecular Weight:379.49
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SRI 6409-94 leads to reductions in mean fetal body weight and in the numbers of ossified skeletal districts, significantly[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 127697-58-9
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Appearance Solid
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Molecular Weight 379.49
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Formula C24H29NO3
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Color Light yellow to brown
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SMILES
O=C(NC1=CC=C(C(OCC)=O)C=C1)C2=CC(C(C)(C)CCC3(C)C)=C3C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (131.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Willhite CC, et al. Structure-activity relationships of retinoids in developmental toxicology. IV. Planar Cisoid conformational restriction. Toxicol Appl Pharmacol. 1990 Apr;103(2):324-44. [Content Brief]
[2]. Willhite CC, et al. Structure-affinity relationships of retinoids with embryonic cellular retinoic acid-binding protein. Toxicol Appl Pharmacol. 1992 Jan;112(1):144-53. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.6351 mL | 13.1756 mL | 26.3512 mL | 65.8779 mL |
| 5 mM | 0.5270 mL | 2.6351 mL | 5.2702 mL | 13.1756 mL | |
| 10 mM | 0.2635 mL | 1.3176 mL | 2.6351 mL | 6.5878 mL | |
| 15 mM | 0.1757 mL | 0.8784 mL | 1.7567 mL | 4.3919 mL | |
| 20 mM | 0.1318 mL | 0.6588 mL | 1.3176 mL | 3.2939 mL | |
| 25 mM | 0.1054 mL | 0.5270 mL | 1.0540 mL | 2.6351 mL | |
| 30 mM | 0.0878 mL | 0.4392 mL | 0.8784 mL | 2.1959 mL | |
| 40 mM | 0.0659 mL | 0.3294 mL | 0.6588 mL | 1.6469 mL | |
| 50 mM | 0.0527 mL | 0.2635 mL | 0.5270 mL | 1.3176 mL | |
| 60 mM | 0.0439 mL | 0.2196 mL | 0.4392 mL | 1.0980 mL | |
| 80 mM | 0.0329 mL | 0.1647 mL | 0.3294 mL | 0.8235 mL | |
| 100 mM | 0.0264 mL | 0.1318 mL | 0.2635 mL | 0.6588 mL |
SRI 6409-94 Related Classifications
HY-147251 Related Classifications
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