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Cat. No.: HY-19956R

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GI254023X (Standard)

Name: GI254023X (Standard)
Brand: MedChemExpress
SKU: HY-19956R
Availability: PreOrder

(Synonyms: GI4023 (Standard); SRI028594 (Standard))

GI254023X (Standard) is the analytical standard of GI254023X (HY-19956). This product is intended for research and analytical applications. GI254023X is a potent MMP9 and ADAM10 inhibitor with IC₅₀s of 2.5 and 5.3 nM, respectively.

For research use only. We do not sell to patients.

CAS No.: 260264-93-5
Formula: C₂₁H₃₃N₃O₄
Molecular Weight:391.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GI254023X (Standard) Chemical Structure

CAS No.: 260264-93-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 260264-93-5
Molecular Weight 391.50
Formula C₂₁H₃₃N₃O₄
SMILES

O=C(N[C@H](C(NC)=O)C(C)(C)C)[C@@H]([C@@H](N(C=O)O)C)CCCC1=CC=CC=C1
Synonyms

GI4023 (Standard); SRI028594 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Verena V. Metz, et al. Induction of RAGE Shedding by Activation of G Protein-Coupled Receptors. PLoS One. 2012. [Content Brief]

[2]. M J M Gooden, et al. Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity. British Journal of Cancer (2014) 110, 1535–1544. [Content Brief]

[3]. N Milosch, et al. Holo-APP and G-protein-mediated signaling are required for sAPPa-induced activation of the Akt. Cell Death Dis. 2014 Aug 28;5:e1391. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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