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SRI-37330 hydrochloride 

Cat. No.: HY-141623 Purity: 99.05%
Handling Instructions

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research.

For research use only. We do not sell to patients.

SRI-37330 hydrochloride Chemical Structure

SRI-37330 hydrochloride Chemical Structure

CAS No. : 2322245-49-6

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Description

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research[1].

IC50 & Target

TXNIP[1]

Molecular Weight

424.87

Formula

C16H20ClF3N4O2S

CAS No.
SMILES

O=S(NCC1CN(CCC1)C2=C3C=C(C(F)(F)F)C=CC3=NC=N2)(C)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (147.10 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3537 mL 11.7683 mL 23.5366 mL
5 mM 0.4707 mL 2.3537 mL 4.7073 mL
10 mM 0.2354 mL 1.1768 mL 2.3537 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
SRI-37330 hydrochloride
Cat. No.:
HY-141623
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