KRR1 - KRR1 small subunit processome component homolog Gene

Also Known as HRB2; RIP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11103

About KRR1

Cytogenetic location: 12q21.2 Genomic coordinates (GRCh38): 12:75,490,863-75,511,609 (from NCBI)

This gene has 5 transcripts (splice variants) and 223 orthologues. Ubiquitous expression in appendix (RPKM 20.3), bone marrow (RPKM 19.6) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in chromosome; intercellular bridge; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

KRR1 Products (1)

mRNA Protein Name
NM_007043.7 NP_008974.5 KRR1 small subunit processome component homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19590578 GOA
Biological Process GO Annotation Evidence References Source
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence References Source
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRR1 Protein Structure

KH_1

KH_1: KH domain (162 - 204)

  • 0
  • 100
  • 200
  • 300
  • 381 a.a.
Protein Preferred Names Protein Names

KRR1 small subunit processome component homolog

  • HIV-1 Rev-binding protein 2

KRR1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KRR1 Q13601 ZBP1 Homo sapiens Q9H171
Anti Tag CoIP
19590578
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Duodenum Adenoma
Duodenal Benign Neoplasm

  • Neoplasm Of Duodenum

  • Neoplasm Of The Duodenum

  • Cancer Of Duodenum
Colorectal Cancer, Hereditary Nonpolyposis, Type 7

  • HNPCC7

  • Hereditary Nonpolyposis Colorectal Cancer Type 7

  • Hereditary Non-Polyposis Colorectal Cancer 7

  • Cancer, Colorectal, Nonpolyposis, Hereditary, Type 7
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07432 KRR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta KRR1 VGNC VGNC:74182
Bos taurus KRR1 VGNC VGNC:30715
Felis catus KRR1 VGNC VGNC:67646
Rattus norvegicus KRR1 RGD RGD:1306183
Mus musculus KRR1 MGD MGI:1289274
Others KRR1 NCBI