STK38 - serine/threonine kinase 38 Gene

Homo sapiens

Also known as NDR; NDR1

Gene ID: 11329 | Gene type: protein coding

About STK38

Cytogenetic location: 6p21.31 Genomic coordinates (GRCh38): 6:36,493,892-36,547,479 (from NCBI)

This gene has 1 transcript (splice variant), 250 orthologues and 1 paralogue. Ubiquitous expression in urinary bladder (RPKM 16.7), colon (RPKM 16.2) and 25 other tissues.

Summary

This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and Apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

STK38 Products(2)

mRNA	Protein	Name
NM_001305102.2	NP_001292031.1	serine/threonine-protein kinase 38
NM_007271.4	NP_009202.1	serine/threonine-protein kinase 38

STK38 Protein Structure

Pkinase

Pkinase_C

0
100
200
300
400
465 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase 38

NDR1 protein kinase

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-10211	Tanespimycin		99.07%	Phase 3

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13938	STK38 Human Pre-designed siRNA Set A		/	Unkown
HY-RS13939	STK38L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	STK38	VGNC	VGNC:46919
Felis catus	STK38	VGNC	VGNC:65786
Mus musculus	STK38	MGD	MGI:2442572
Rattus norvegicus	STK38	RGD	RGD:1309455
Macaca mulatta	STK38	VGNC	VGNC:78155
Bos taurus	STK38	VGNC	VGNC:35399

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