2. Gene
  3. SLC2A13 - solute carrier family 2 member 13 Gene

SLC2A13 - solute carrier family 2 member 13 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HMIT

Gene ID: 114134 | Gene type: protein coding

About SLC2A13

Cytogenetic location: 12q12 Genomic coordinates (GRCh38): 12:39,755,025-40,106,081 (from NCBI)

This gene has 4 transcripts (splice variants), 314 orthologues and 13 paralogues. Broad expression in brain (RPKM 11.8), kidney (RPKM 3.4) and 21 other tissues.

Summary

Enables ATPase binding activity; myo-inositol:proton symporter activity; and protease binding activity. Involved in myo-inositol transport and positive regulation of amyloid-beta formation. Is integral component of plasma membrane. Part of cell body; cell periphery; and cell projection. [provided by Alliance of Genome Resources, Apr 2022]

SLC2A13 Products(1)

mRNA Protein Name
NM_052885.4 NP_443117.3 proton myo-inositol cotransporter

SLC2A13 Protein Structure

Sugar_tr

Sugar_tr: Sugar (and other) transporter (84 - 414)

Sugar_tr

Sugar_tr: Sugar (and other) transporter (506 - 609)

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  • 648 a.a.
Protein Preferred Names Protein Names

proton myo-inositol cotransporter

H(+)-myo-inositol symporter

Related Diseases

Diseases Alias
Retinitis Pigmentosa 32

RP32

Retinitis Pigmentosa-32
Amyotrophic Lateral Sclerosis Type 5

Amyotrophic Lateral Sclerosis 5

Als5
Arterial Tortuosity Syndrome

Arterial Tortuosity

Ats

ATORS

Tortuosity, Arterial, Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13162 SLC2A13 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC2A13 VGNC VGNC:34799
Rattus norvegicus SLC2A13 RGD RGD:621814
Mus musculus SLC2A13 MGD MGI:2146030
Canis familiaris SLC2A13 VGNC VGNC:46340
Macaca mulatta SLC2A13 VGNC VGNC:77491