2. Gene
  3. ERMAP - erythroblast membrane associated protein (Scianna blood group) Gene

ERMAP - erythroblast membrane associated protein (Scianna blood group) Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RD; SC; BTN5; PRO2801

Gene ID: 114625 | Gene type: protein coding

About ERMAP

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:42,817,122-42,844,991 (from NCBI)

This gene has 9 transcripts (splice variants), 99 orthologues, 15 paralogues and is associated with 2 phenotypes. Ubiquitous expression in bone marrow (RPKM 13.2), thyroid (RPKM 8.4) and 25 other tissues.

Summary

The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

ERMAP Products(2)

mRNA Protein Name
NM_001017922.2 NP_001017922.1 erythroid membrane-associated protein precursor
NM_018538.4 NP_061008.2 erythroid membrane-associated protein precursor

ERMAP Protein Structure

V-set

V-set: Immunoglobulin V-set domain (40 - 133)

PRY

PRY: SPRY-associated domain (240 - 288)

SPRY

SPRY: SPRY domain (291 - 395)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 475 a.a.
Protein Preferred Names Protein Names

erythroid membrane-associated protein

Radin blood group (Rd)

Recombinant ERMAP Proteins

Cat. No. Product Name Accession Purity
HY-P70896 ERMAP Protein, Human (HEK293, His) Q96PL5 (H30-A155) ≥95%

Related Diseases

Diseases Alias
Radin Blood Group Antigen

RD

Blood Group--Radin Antigen
Scarlet Fever

Scarlatina

Scarlatina Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04503 ERMAP Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ERMAP VGNC VGNC:99910
Felis catus ERMAP VGNC VGNC:80201
Mus musculus ERMAP MGD MGI:1349816
Rattus norvegicus ERMAP RGD RGD:1309996
Others ERMAP NCBI