Usp2 - ubiquitin specific peptidase 2 Gene

Also Known as UBP-t

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 115771

Summary

Enables thiol-dependent Deubiquitinase. Involved in negative regulation of skeletal muscle tissue development; positive regulation of skeletal muscle tissue development; and protein deubiquitination. Located in centrosome; nucleus; and perinuclear region of cytoplasm. Orthologous to human USP2 (ubiquitin specific peptidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Usp2 Products (1)

mRNA Protein Name
NM_053774.3 NP_446226.3 ubiquitin carboxyl-terminal hydrolase 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cysteine-type deubiquitinase activity IMP
IMP: Inferred from mutant phenotype
10938131 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23213472 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of skeletal muscle tissue development IDA
IDA: Inferred from direct assay
10938131 RGD
involved in positive regulation of skeletal muscle tissue development IDA
IDA: Inferred from direct assay
10938131 RGD
involved in protein deubiquitination IDA
IDA: Inferred from direct assay
10938131 RGD
involved in protein deubiquitination IMP
IMP: Inferred from mutant phenotype
23213472 RGD
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
10938131 RGD
located in nucleus IDA
IDA: Inferred from direct assay
10938131 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
10938131 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 2

  • 41 kDa ubiquitin-specific protease

  • deubiquitinating enzyme 2

  • ubiquitin specific protease 2

  • ubiquitin thioesterase 2

  • ubiquitin thiolesterase 2

  • ubiquitin-specific-processing protease 2

  • ubiquitin-specific-processing protease testis

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162312 LLK203 Inhibitor 98.58% Unkown
HY-RS15530 USP2 Human Pre-designed siRNA Set A Inhibitor / Unkown
HY-179630 MS102 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp2 NCBI NCBI:9099