Mprip - myosin phosphatase Rho interacting protein Gene

Also Known as Mrip; M-rip; Rhoip3; p116Rip

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116504

Summary

Predicted to enable actin filament binding activity. Involved in maintenance of protein location in cell; negative regulation of myosin-light-chain-phosphatase activity; and positive regulation of protein phosphorylation. Located in stress fiber. Orthologous to human MPRIP (myosin Phosphatase Rho interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Mprip Products (4)

mRNA Protein Name
NM_001034022.2 NP_001029194.1 myosin phosphatase Rho-interacting protein isoform 3
NM_001371051.2 NP_001357980.1 myosin phosphatase Rho-interacting protein isoform 1
NM_001414223.1 NP_001401152.1 myosin phosphatase Rho-interacting protein isoform 4
NM_053814.3 NP_446266.2 myosin phosphatase Rho-interacting protein isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in maintenance of protein location in cell IMP
IMP: Inferred from mutant phenotype
17661354 RGD
involved in protein dephosphorylation IMP
IMP: Inferred from mutant phenotype
17661354 RGD
Cellular Component GO Annotation Evidence References Source
located in stress fiber IDA
IDA: Inferred from direct assay
17661354 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin phosphatase Rho-interacting protein

  • RIP3

  • Rho interacting protein 3

  • rho-interacting protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174330 TRK-IN-31 Inhibitor / Unkown
HY-174330A TRK-IN-31 hydrochloride Inhibitor / Unkown
HY-RS08629 MPRIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21654 Mprip Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28172 Mprip Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mprip NCBI NCBI:23164