CLRN3 - clarin 3 Gene

Also Known as TMEM12; USH3AL1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 119467

About CLRN3

This gene has 1 transcript (splice variant), 198 orthologues and 2 paralogues. Biased expression in small intestine (RPKM 43.6), colon (RPKM 38.2) and 5 other tissues.

Summary

Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

CLRN3 Products (1)

mRNA Protein Name
NM_152311.5 NP_689524.1 clarin-3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLRN3 Protein Structure

Claudin_2

Claudin_2: PMP-22/EMP/MP20/Claudin tight junction (20 - 199)

  • 0
  • 100
  • 200
  • 226 a.a.
Protein Preferred Names Protein Names

clarin-3

  • transmembrane protein 12

CLRN3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CLRN3 Q8NCR9 NME2P1 Homo sapiens O60361
Anti Tag CoIP
28514442
Intra
CLRN3 Q8NCR9 NME2P1 Homo sapiens O60361
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Usher Syndrome, Type Iiia

  • Usher Syndrome Type 3

  • Ush3

  • Usher Syndrome Type 3a

  • USH3A

  • Usher Syndrome, Type Iii

  • Usher Syndrome, Type 3

  • Usher Syndrome, Type 3a

  • Usher Syndrome Type Iiia

  • Usher Syndrome 3a

  • Usher'S Syndrome Type 3

  • Usher Syndrome Iii

  • Usher Syndrome Type Iii
Usher Syndrome

  • Deafness-Retinitis Pigmentosa Syndrome

  • Dystrophia Retinae Pigmentosa-Dysostosis Syndrome

  • Graefe-Usher Syndrome

  • Hallgren Syndrome

  • Usher'S Syndrome

  • Retinitis Pigmentosa-Deafness Syndrome

  • Retinitis Pigmentosa-Hearing Loss Syndrome

  • Ush

  • Usher Syndromes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02838 CLRN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CLRN3 VGNC VGNC:27464
Canis familiaris CLRN3 VGNC VGNC:39361
Rattus norvegicus CLRN3 RGD RGD:1305043
Mus musculus CLRN3 MGD MGI:2142022
Macaca mulatta CLRN3 VGNC VGNC:106025
Others CLRN3 NCBI