Calb2 - calbindin 2 Gene

Also Known as CR

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12308

Summary

Enables calcium ion binding activity involved in regulation of presynaptic cytosolic calcium ion concentration. Predicted to be involved in regulation of long-term synaptic potentiation and regulation of presynaptic cytosolic calcium ion concentration. Located in gap junction. Is active in parallel fiber to Purkinje cell synapse. Is expressed in several structures, including alimentary system; nervous system; reproductive system; respiratory system; and sensory organ. Orthologous to human CALB2 (calbindin 2). [provided by Alliance of Genome Resources, Apr 2022]

Calb2 Products (3)

mRNA Protein Name
NM_001368293.1 NP_001355222.1 calretinin isoform 2
NM_001368294.1 NP_001355223.1 calretinin isoform 3
NM_007586.2 NP_031612.1 calretinin isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
23273895 MGI
enables calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
23273895 MGI
Cellular Component GO Annotation Evidence References Source
located in gap junction IDA
IDA: Inferred from direct assay
12868005 MGI
is active in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
23273895 MGI
is active in parallel fiber to Purkinje cell synapse IMP
IMP: Inferred from mutant phenotype
23273895 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calretinin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01827 CALB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20868 Calb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27385 Calb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Calb2 NCBI NCBI:794