INO80C - INO80 complex subunit C Gene

Also Known as IES6; hIes6; C18orf37

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 125476

Summary

Involved in several processes, including positive regulation of DNA-templated transcription; regulation of DNA metabolic process; and regulation of chromosome organization. Located in fibrillar center and nucleoplasm. Part of Ino80 complex and MLL1 complex. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in testis (RPKM 20.7), esophagus (RPKM 7.5) and 24 other tissues.

INO80C Products (3)

mRNA Protein Name
NM_001098817.2 NP_001092287.1 INO80 complex subunit C isoform 1
NM_001308064.2 NP_001294993.1 INO80 complex subunit C isoform 3
NM_194281.4 NP_919257.2 INO80 complex subunit C isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26496610 GOA
Biological Process GO Annotation Evidence References Source
involved in chromatin remodeling IDA
IDA: Inferred from direct assay
21303910 GOA
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
27641337 GOA
involved in regulation of DNA replication IMP
IMP: Inferred from mutant phenotype
25016522 GOA
involved in regulation of DNA strand elongation IMP
IMP: Inferred from mutant phenotype
25016522 GOA
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
26340092 GOA
involved in regulation of chromosome organization IMP
IMP: Inferred from mutant phenotype
26340092 GOA
Cellular Component GO Annotation Evidence References Source
part of Ino80 complex IDA
IDA: Inferred from direct assay
21303910 GOA
part of MLL1 complex IDA
IDA: Inferred from direct assay
15960975 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

INO80C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
INO80C Q6PI98 TGFBR2 Homo sapiens P37173
Y2H Array
32814053
Intra
INO80C Q6PI98 TGFBR2 Homo sapiens P37173
Y2H Pooling
32814053
Intra
INO80C Q6PI98 TGFBR2 Homo sapiens P37173
Validated Y2H
32814053
Intra
INO80C Q6PI98 SERPINH1 Homo sapiens P50454
Y2H Array
32814053
Intra
INO80C Q6PI98 SERPINH1 Homo sapiens P50454
Validated Y2H
32814053
Intra
INO80C Q6PI98 SERPINH1 Homo sapiens P50454
Y2H Pooling
32814053
Intra
INO80C Q6PI98 ACTR5 Homo sapiens Q9H9F9
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06821 INO80 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06822 INO80D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06823 INO80E Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19697 Ino80 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26192 Ino80 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown