Cdkn2d - cyclin dependent kinase inhibitor 2D Gene

Also Known as p19; INK4d; p19INK4d

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12581

Summary

Enables protein kinase binding activity. Acts upstream of or within negative regulation of cell cycle G1/S phase transition and sensory perception of sound. Part of cyclin D2-CDK4 complex. Is expressed in several structures, including central nervous system; genitourinary system; liver lobe; retina; and trigeminal nerve. Orthologous to human CDKN2D (cyclin dependent kinase inhibitor 2D). [provided by Alliance of Genome Resources, Apr 2022]

Cdkn2d Products (4)

mRNA Protein Name
NM_001409664.1 NP_001396593.1 cyclin-dependent kinase 4 inhibitor D isoform 1
NM_001409665.1 NP_001396594.1 cyclin-dependent kinase 4 inhibitor D isoform 2
NM_001409666.1 NP_001396595.1 cyclin-dependent kinase 4 inhibitor D isoform 2
NM_009878.4 NP_034008.2 cyclin-dependent kinase 4 inhibitor D isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein kinase binding IPI
IPI: Inferred from physical interaction
7739547 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of cell cycle G1/S phase transition IDA
IDA: Inferred from direct assay
7739547 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
12717441 MGI
Cellular Component GO Annotation Evidence References Source
part of cyclin D2-CDK4 complex IDA
IDA: Inferred from direct assay
7739547 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclin-dependent kinase 4 inhibitor D

  • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

  • p19-INK4d

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02418 CDKN2D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20141 Cdkn2d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26645 Cdkn2d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdkn2d NCBI NCBI:1032