TMEM150A - transmembrane protein 150A Gene

Also Known as TTN1; DRAM5; TM6P1; TMEM150

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 129303

Summary

Involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in placenta (RPKM 10.3), kidney (RPKM 7.9) and 24 other tissues.

TMEM150A Products (3)

mRNA Protein Name
NM_001031738.3 NP_001026908.1 transmembrane protein 150A isoform 1 precursor
NM_001369917.1 NP_001356846.1 transmembrane protein 150A isoform 1 precursor
NM_153342.4 NP_699173.2 transmembrane protein 150A isoform 2
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Références Source
involved in phosphatidylinositol phosphate biosynthetic process IMP
IMP: Inferred from mutant phenotype
25608530 GOA
involved in protein localization to plasma membrane IDA
IDA: Inferred from direct assay
25608530 GOA
Cellular Component GO Annotation Evidence Références Source
located in plasma membrane IDA
IDA: Inferred from direct assay
25608530 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM150A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
TMEM150A Q86TG1 KRTAP10-8 Homo sapiens P60410 25416956
Intra
TMEM150A Q86TG1 ADAMTSL4 Homo sapiens Q6UY14-3 25416956
Intra
TMEM150A Q86TG1 NOTCH2NLC Homo sapiens P0DPK4 32296183
Intra
TMEM150A Q86TG1 NOTCH2NLC Homo sapiens P0DPK4 32296183
Intra
TMEM150A Q86TG1 TRIM42 Homo sapiens Q8IWZ5 32296183
Intra
TMEM150A Q86TG1 TRIM42 Homo sapiens Q8IWZ5 32296183
Intra
TMEM150A Q86TG1 TRIM42 Homo sapiens Q8IWZ5 32296183
Intra
TMEM150A Q86TG1 NOTCH2NLA Homo sapiens Q7Z3S9 25416956
Intra
TMEM150A Q86TG1 NOTCH2NLA Homo sapiens Q7Z3S9 25416956
Cross: Cross-species interaction Intra: Intraspecies interaction