CMPK2 - cytidine/uridine monophosphate kinase 2 Gene

Also Known as NDK; TYKi; TMPK2; UMP-CMPK2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 129607

About CMPK2

Cytogenetic location: 2p25.2 Genomic coordinates (GRCh38): 2:6,840,553-6,866,635 (from NCBI)

This gene has 7 transcripts (splice variants), 175 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 6.8), spleen (RPKM 4.2) and 23 other tissues.

Summary

This gene encodes one of the Enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

CMPK2 Products (3)

mRNA Protein Name
NM_001256477.1 NP_001243406.1 UMP-CMP kinase 2, mitochondrial isoform 2 precursor
NM_001256478.1 NP_001243407.1 UMP-CMP kinase 2, mitochondrial isoform 3 precursor
NM_207315.4 NP_997198.2 UMP-CMP kinase 2, mitochondrial isoform 1 precursor

CMPK2 Protein Structure

Thymidylate_kin

Thymidylate_kin: Thymidylate kinase (257 - 436)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 449 a.a.
Protein Preferred Names Protein Names

UMP-CMP kinase 2, mitochondrial

  • UMP/CMP kinase

Related Diseases

Diseases Alias
Neuroaspergillosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18808 Cmpk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02862 CMPK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25298 Cmpk2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CMPK2 VGNC VGNC:71362
Mus musculus CMPK2 MGD MGI:99830
Rattus norvegicus CMPK2 RGD RGD:1305881
Bos taurus CMPK2 VGNC VGNC:27481
Others CMPK2 NCBI