2. Gene
  3. AADAC - arylacetamide deacetylase Gene

AADAC - arylacetamide deacetylase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DAC; CES5A1

Gene ID: 13 | Gene type: protein coding

About AADAC

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:151,814,116-151,828,488 (from NCBI)

This gene has 2 transcripts (splice variants), 214 orthologues and 5 paralogues. Biased expression in liver (RPKM 174.6), small intestine (RPKM 100.2) and 4 other tissues.

Summary

Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]

AADAC Products(1)

mRNA Protein Name
NM_001086.3 NP_001077.2 arylacetamide deacetylase

AADAC Protein Structure

Abhydrolase_3

Abhydrolase_3: alpha/beta hydrolase fold (107 - 259)

Abhydrolase_3

Abhydrolase_3: alpha/beta hydrolase fold (316 - 376)

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  • 399 a.a.
Protein Preferred Names Protein Names

arylacetamide deacetylase

arylacetamide deacetylase (esterase)

Recombinant AADAC Proteins

Cat. No. Product Name Accession Purity
HY-P72067 AADAC Protein, Human (His-SUMO) P22760 (P24-L399) ≥95%

Related Diseases

Diseases Alias
Chronic Tic Disorder

Chronic Motor Or Vocal Tic Disorder

Tic Disorders

Tic Disorder

Tic Disorder Nos

Tic Nos

Tic Spasm Nos
Tic Disorder

Tics

Behavioral Tic
Gilles De La Tourette Syndrome

Tourette Syndrome

Tourette Disorder

GTS

Ts

Gilles De La Tourette'S Syndrome

Motor-Verbal Tic Disorder

Guinon'S Disease

Psychogenic Tics

Tourette'S Syndrome

Chronic Motor And Vocal Tic Disorder

Td

Tourette'S Disease

Combined Vocal And Multiple Motor Tic Disorder [De La Tourette]

Combined Vocal And Multiple Motor Tic Disorder

Tic De La Tourette
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00017 AADAC Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta AADAC VGNC VGNC:81172
Mus musculus AADAC MGD MGI:1915008
Canis familiaris AADAC VGNC VGNC:37404
Rattus norvegicus AADAC RGD RGD:631440
Others AADAC NCBI