AAMP - angio associated migratory cell protein Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 14

About AAMP

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:218,264,129-218,270,137 (from NCBI)

This gene has 10 transcripts (splice variants), 204 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 40.5), thyroid (RPKM 38.1) and 25 other tissues.

Summary

The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. [provided by RefSeq, Oct 2014]

AAMP Products (2)

mRNA Protein Name
NM_001087.5 NP_001078.2 angio-associated migratory cell protein isoform 2
NM_001302545.2 NP_001289474.1 angio-associated migratory cell protein isoform 1

AAMP Protein Structure

WD40

WD40: WD domain, G-beta repeat (86 - 119)

WD40

WD40: WD domain, G-beta repeat (125 - 161)

WD40

WD40: WD domain, G-beta repeat (209 - 243)

WD40

WD40: WD domain, G-beta repeat (256 - 286)

WD40

WD40: WD domain, G-beta repeat (356 - 386)

WD40

WD40: WD domain, G-beta repeat (392 - 427)

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  • 434 a.a.
Protein Preferred Names Protein Names

angio-associated migratory cell protein

AAMP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
AAMP Q13685 AEN Homo sapiens Q8WTP8-2
Anti Tag CoIP
28514442
Intra
AAMP Q13685 AEN Homo sapiens Q8WTP8-2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

AAMP Antibodies

Cat. No. Product Name Application Reactivity
HY-P82218 AAMP Antibody (YA1963) WB Human, Mouse, Rat
HY-P82218A AAMP Antibody (YA1963)(PBS only) WB Human, Mouse, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00024 AAMP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus AAMP VGNC VGNC:59452
Canis familiaris AAMP VGNC VGNC:37412
Mus musculus AAMP MGD MGI:107809
Bos taurus AAMP VGNC VGNC:25445
Macaca mulatta AAMP VGNC VGNC:69455
Rattus norvegicus AAMP RGD RGD:1306281
Others AAMP NCBI