Fgf18 - fibroblast growth factor 18 Gene

Also Known as Fgf6a; FGF-18; D130055P09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14172

Summary

Predicted to enable growth factor activity; type 1 Fibroblast Growth Factor receptor binding activity; and type 2 Fibroblast Growth Factor receptor binding activity. Acts upstream of or within several processes, including positive regulation of chondrocyte differentiation; positive regulation of signal transduction; and skeletal system development. Predicted to be located in nucleolus. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; sensory organ; and skeleton. Orthologous to human FGF18 (Fibroblast Growth Factor 18). [provided by Alliance of Genome Resources, Apr 2022]

Fgf18 Products (1)

mRNA Protein Name
NM_008005.2 NP_032031.1 fibroblast growth factor 18 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
11741978 MGI
acts upstream of or within angiogenesis IMP
IMP: Inferred from mutant phenotype
17014841 MGI
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17014841 MGI
acts upstream of or within chondrocyte development IMP
IMP: Inferred from mutant phenotype
17014841 MGI
acts upstream of chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
15781473 MGI
acts upstream of or within endochondral ossification IMP
IMP: Inferred from mutant phenotype
17014841 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
15781473 MGI
acts upstream of or within intramembranous ossification IMP
IMP: Inferred from mutant phenotype
17014841 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
15336546 MGI
acts upstream of or within ossification IMP
IMP: Inferred from mutant phenotype
11937493 MGI
acts upstream of or within positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
11741978 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17014841 MGI
acts upstream of or within positive regulation of chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
15781473 MGI
acts upstream of or within positive regulation of vascular endothelial growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
17014841 MGI
acts upstream of vascular endothelial growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
17014841 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 18

  • fibroblast growth factor 6a

  • zFGF5

Recombinant Fgf18 Proteins

Cat. No. Product Name Accession Purity
HY-P7171 FGF-18 Protein, Mouse O89101 (E28-G207) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75192 FGF-18 Protein, Mouse (HEK293, His) O89101 (E28-G207) ≥ 95%, as determined by reducing SDS-PAGE.

Fgf18 Antibodies

Cat. No. Product Name Application Reactivity
HY-P86878 FGF18 Antibody (YA6571) WB Mouse

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS23652 Fgf18 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04894 FGF18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174704 Human FGF18 mRNA / Unkown
HY-RS17200 Fgf18 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf18 NCBI NCBI:8817