Fgf4 - fibroblast growth factor 4 Gene

Also Known as KS3; hst; Fgfk; Hst1; kFGF; Fgf-4; Fgf7a; hst-1; HBGF-4; Hstf-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14175

Summary

Predicted to enable Fibroblast Growth Factor receptor binding activity and growth factor activity. Acts upstream of or within several processes, including animal organ morphogenesis; cellular response to leukemia inhibitory factor; and positive regulation of macromolecule metabolic process. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including branchial pouch; cerebellum; embryo mesenchyme; surface ectoderm; and tooth. Orthologous to human FGF4 (Fibroblast Growth Factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Fgf4 Products (1)

mRNA Protein Name
NM_010202.6 NP_034332.2 fibroblast growth factor 4 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
8393815 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of apoptotic process IGI
IGI: Inferred from genetic interaction
16245339 MGI
acts upstream of or within apoptotic process involved in morphogenesis IGI
IGI: Inferred from genetic interaction
15649466 MGI
acts upstream of or within cartilage condensation IGI
IGI: Inferred from genetic interaction
8565825 MGI
acts upstream of cell population proliferation IGI
IGI: Inferred from genetic interaction
16245339 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within cranial suture morphogenesis IDA
IDA: Inferred from direct assay
9477322 MGI
acts upstream of or within embryonic hindlimb morphogenesis IGI
IGI: Inferred from genetic interaction
16245339 MGI
acts upstream of or within embryonic limb morphogenesis IGI
IGI: Inferred from genetic interaction
15328019 MGI
acts upstream of or within epithelial cell apoptotic process IGI
IGI: Inferred from genetic interaction
15649466 MGI
acts upstream of or within negative regulation of apoptotic process IGI
IGI: Inferred from genetic interaction
16245339 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IDA
IDA: Inferred from direct assay
12502739 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
17951031 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
9244299 MGI
acts upstream of or within positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
19289495 MGI
acts upstream of or within positive regulation of stem cell proliferation IGI
IGI: Inferred from genetic interaction
16245339 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9477322 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
8898217 MGI
acts upstream of or within regulation of gene expression IDA
IDA: Inferred from direct assay
19289495 MGI
acts upstream of or within somatic stem cell population maintenance IGI
IGI: Inferred from genetic interaction
15328412 MGI
acts upstream of or within stem cell population maintenance IGI
IGI: Inferred from genetic interaction
15328412 MGI
acts upstream of stem cell proliferation IGI
IGI: Inferred from genetic interaction
16245339 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 4

  • K-fibroblast growth factor

  • fibroblast growth factor 7a

  • heparin-binding growth factor 4

Recombinant Fgf4 Proteins

Cat. No. Product Name Accession Purity
HY-P72649 FGF-4 Protein, Mouse P11403 (S67-L202) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04902 FGF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174696 Human FGF4 mRNA / Unkown
HY-RS16649 Fgf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23084 Fgf4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf4 NCBI NCBI:2249