Fhl3 - four and a half LIM domains 3 Gene

Also Known as SLIM2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14201

Summary

Enables actin binding activity. Acts upstream of or within actin Cytoskeleton organization. Located in Z disc; nucleus; and stress fiber. Is expressed in several structures, including genitourinary system; heart; lung; skeletal muscle; and thymus. Orthologous to human FHL3 (four and a half LIM domains 3). [provided by Alliance of Genome Resources, Apr 2022]

Fhl3 Products (1)

mRNA Protein Name
NM_010213.3 NP_034343.2 four and a half LIM domains protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
12704194 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17363903 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin cytoskeleton organization IDA
IDA: Inferred from direct assay
12704194 MGI
Cellular Component GO Annotation Evidence References Source
located in Z disc IDA
IDA: Inferred from direct assay
12704194 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12704194 MGI
located in stress fiber IDA
IDA: Inferred from direct assay
12704194 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

four and a half LIM domains protein 3

  • skeletal muscle LIM-protein 2

Fhl3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Fhl3 Q9R059 Sox15 Mus musculus P43267
Y2H
17363903
Intra
Fhl3 Q9R059 Sox15 Mus musculus P43267
Pull Down
17363903
Intra
Fhl3 Q9R059 Sox15 Mus musculus P43267
Anti Tag CoIP
17363903
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N6896 Isoviolanthin Inhibitor 99.87% Unkown
HY-RS04936 FHL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15467 UNC13D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20733 Fhl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27245 Fhl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fhl3 NCBI NCBI:2275