ALG10B - ALG10 alpha-1,2-glucosyltransferase B Gene

Also Known as KCR1; ALG10

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 144245

Summary

Enables transferase activity. Involved in positive regulation of inward rectifier Potassium Channel activity; positive regulation of protein glycosylation; and protein glycosylation. Located in endoplasmic reticulum. Implicated in long QT syndrome 2. [provided by Alliance of Genome Resources, Apr 2022]

ALG10B Products (1)

mRNA Protein Name
NM_001013620.4 NP_001013642.2 dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity IGI
IGI: Inferred from genetic interaction
20950623 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Referencias Source
involved in dolichol-linked oligosaccharide biosynthetic process IGI
IGI: Inferred from genetic interaction
20950623 GOA
involved in protein N-linked glycosylation IGI
IGI: Inferred from genetic interaction
20950623 GOA
Cellular Component GO Annotation Evidence Referencias Source
is active in endoplasmic reticulum membrane IGI
IGI: Inferred from genetic interaction
20950623 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
14525949 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

  • ALG10B, alpha-1,2-glucosyltransferase

  • alpha-1,2-glucosyltransferase ALG10-A

  • alpha-2-glucosyltransferase ALG10-B

  • asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase)

  • asparagine-linked glycosylation 10, alpha-1,2-glucosylt

ALG10B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Referencias
Intra
ALG10B Q5I7T1 SHISAL1 Homo sapiens Q3SXP7
Y2H Array
32296183
Intra
ALG10B Q5I7T1 SHISAL1 Homo sapiens Q3SXP7
Y2H Prey Pooling
32296183
Intra
ALG10B Q5I7T1 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra
ALG10B Q5I7T1 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS00587 ALG10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown