ETFRF1 - electron transfer flavoprotein regulatory factor 1 Gene

Also Known as LYRM5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 144363

Summary

Enables enzyme inhibitor activity. Involved in negative regulation of Oxidative Phosphorylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in testis (RPKM 14.3), adrenal (RPKM 11.7) and 25 other tissues.

ETFRF1 Products (1)

mRNA Protein Name
NM_001001660.3 NP_001001660.2 electron transfer flavoprotein regulatory factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27499296 GOA
Biological Process GO Annotation Evidence References Source
involved in respiratory electron transport chain IMP
IMP: Inferred from mutant phenotype
27499296 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
27499296 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ETFRF1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ETFRF1 Q6IPR1 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra
ETFRF1 Q6IPR1 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra
ETFRF1 Q6IPR1 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra
ETFRF1 Q6IPR1 ETFB Homo sapiens P38117
Anti Tag CoIP
33961781
Intra
ETFRF1 Q6IPR1 ETFB Homo sapiens P38117
Pull Down
27499296
Intra
ETFRF1 Q6IPR1 ETFB Homo sapiens P38117
Anti Tag CoIP
27499296
Intra
ETFRF1 Q6IPR1 AGTRAP Homo sapiens Q6RW13-2
Y2H Array
32296183
Intra
ETFRF1 Q6IPR1 AGTRAP Homo sapiens Q6RW13-2
Y2H Prey Pooling
32296183
Intra
ETFRF1 Q6IPR1 AGTRAP Homo sapiens Q6RW13-2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction