CIART - circadian associated repressor of transcription Gene

Also Known as GM129; CHRONO; C1orf51

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 148523

About CIART

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,282,554-150,287,093 (from NCBI)

This gene has 7 transcripts (splice variants) and 216 orthologues. Broad expression in heart (RPKM 6.9), thyroid (RPKM 5.6) and 24 other tissues.

Summary

Predicted to enable E-box binding activity. Predicted to be involved in circadian regulation of gene expression; locomotor rhythm; and negative regulation of transcription, DNA-templated. Predicted to be located in PML body. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CIART Products (5)

mRNA Protein Name
NM_001300838.2 NP_001287767.1 circadian-associated transcriptional repressor isoform a
NM_001300839.2 NP_001287768.1 circadian-associated transcriptional repressor isoform b
NM_001300840.2 NP_001287769.1 circadian-associated transcriptional repressor isoform b
NM_001300841.2 NP_001287770.1 circadian-associated transcriptional repressor isoform b
NM_144697.4 NP_653298.1 circadian-associated transcriptional repressor isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24385426 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

circadian-associated transcriptional repressor

  • chIP-derived repressor of network oscillator

CIART Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
CIART Q8N365 Bmal1 Mus musculus Q9WTL8
Anti Tag CoIP
24737000
Intra
CIART Q8N365 DAB1 Homo sapiens O75553
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Gallbladder Benign Neoplasm
Gallbladder Adenoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02705 CIART Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21529 Ciart Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28047 Ciart Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CIART VGNC VGNC:27358
Felis catus CIART VGNC VGNC:60897
Macaca mulatta CIART VGNC VGNC:71345
Rattus norvegicus CIART RGD RGD:1566380
Mus musculus CIART MGD MGI:2684975
Canis familiaris CIART VGNC VGNC:39265
Others CIART NCBI