HORMAD2 - HORMA domain containing 2 Gene

Homo sapiens

Also known as CT46.2

Gene ID: 150280 | Gene type: protein coding

About HORMAD2

Cytogenetic location: 22q12.2 Genomic coordinates (GRCh38): 22:30,077,732-30,207,456 (from NCBI)

This gene has 4 transcripts (splice variants), 124 orthologues and 1 paralogue. Restricted expression toward testis (RPKM 6.8).

Summary

Predicted to be involved in meiotic sister chromatid cohesion. Located in centrosome; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HORMAD2 Products(3)

mRNA	Protein	Name
NM_001329457.2	NP_001316386.1	HORMA domain-containing protein 2 isoform a
NM_001329458.2	NP_001316387.1	HORMA domain-containing protein 2 isoform b
NM_152510.4	NP_689723.1	HORMA domain-containing protein 2 isoform a

HORMAD2 Protein Structure

HORMA

0
100
200
307 a.a.

Protein Preferred Names

Protein Names

HORMA domain-containing protein 2

Related Diseases

Diseases

Alias

Autoimmune Glomerulonephritis

Nephrotic Syndrome, Type 7

Immunoglobulin-Mediated Membranoproliferative Glomerulonephritis	Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 7
NPHS7	Nephrotic Syndrome Type 7
Ig-Mediated Membranoproliferative Glomerulonephritis	Ig-Mediated Mpgn
Immunoglobulin-Mediated Mpgn	Nephrotic Syndrome, Type 7, With Membranoproliferative Glomerulonephritis
Hemolytic Uremic Syndrome, Atypical 7	Nephrotic Syndrome Type 7 With Membranoptoliferative Glomerulonephritis
Hemolytic Uremic Syndrome With Dgke Deficiency	Hus With Dgke Deficiency
Hemolytic Uremic Syndrome Atypical 7	AHUS7
Nephrotic Syndrome 7	Nephrotic Syndrome Type 7 With Membranoproliferative Glomerulonephritis

Nephronophthisis 3

NPHP3	Nph3
Adolescent Nephronophthisis	Nephronophthisis, Type 3

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06292	HORMAD2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	HORMAD2	VGNC	VGNC:84915
Mus musculus	HORMAD2	MGD	MGI:1923078
Bos taurus	HORMAD2	VGNC	VGNC:53905
Felis catus	HORMAD2	VGNC	VGNC:80442
Rattus norvegicus	HORMAD2	RGD	RGD:1565447
Canis familiaris	HORMAD2	VGNC	VGNC:52934

Name
Email *

	Sorry, but the email address you supplied was invalid.