CX3CR1 - C-X3-C motif chemokine receptor 1 Gene

Also Known as V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1524

About CX3CR1

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:39,263,494-39,292,966 (from NCBI)

This gene has 6 transcripts (splice variants), 259 orthologues, 23 paralogues and is associated with 4 phenotypes. Biased expression in brain (RPKM 21.4), lung (RPKM 6.4) and 12 other tissues.

Summary

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 Infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

CX3CR1 Products (5)

mRNA Protein Name
NM_001171171.2 NP_001164642.1 CX3C chemokine receptor 1 isoform b
NM_001337.4 NP_001328.1 CX3C chemokine receptor 1 isoform b
XM_047447538.1 XP_047303494.1 CX3C chemokine receptor 1 isoform X1
NM_001171174.1 NP_001164645.1 CX3C chemokine receptor 1 isoform a
NM_001171172.2 NP_001164643.1 CX3C chemokine receptor 1 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables C-X3-C chemokine binding IDA
IDA: Inferred from direct assay
23125415 GOA
enables C-X3-C chemokine receptor activity IDA
IDA: Inferred from direct assay
9782118 GOA
enables CX3C chemokine receptor binding IDA
IDA: Inferred from direct assay
9782118 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9931005 GOA
Biological Process GO Annotation Evidence References Source
involved in antifungal innate immune response IMP
IMP: Inferred from mutant phenotype
29326275 GOA
involved in cell adhesion IDA
IDA: Inferred from direct assay
9782118 GOA
involved in chemotaxis IGI
IGI: Inferred from genetic interaction
16019082 GOA
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
28791023 GOA
is active in plasma membrane IDA
IDA: Inferred from direct assay
12055230 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CX3CR1 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (48 - 293)

  • 0
  • 100
  • 200
  • 300
  • 355 a.a.
Protein Preferred Names Protein Names

CX3C chemokine receptor 1

  • C-X3-C CKR-1

  • CMK-BRL-1

  • CMK-BRL1

  • G-protein coupled receptor 13

  • beta chemokine receptor-like 1

  • chemokine (C-C) receptor-like 1

  • chemokine (C-X3-C motif) receptor 1

  • chemokine (C-X3-C) receptor 1

  • fractalkine receptor

CX3CR1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P84354 CX3CR1 Antibody (YA4051) ICC/IF, FC, ELISA Human
HY-P84354A CX3CR1 Antibody (YA4051)(PBS only) ICC/IF, FC, ELISA Human

Related Diseases

Diseases Alias
Fundus Dystrophy

  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal
Atherosclerosis Susceptibility

  • Atherosclerosis

  • Atherosclerosis, Susceptibility To

  • ATHS

  • Atherogenic Lipoprotein Phenotype

  • Alp

  • Arteriosclerosis
Eye Disease

  • Eye Diseases

  • Abnormality Of The Eye

  • Toxoplasma Oculopathy
Degeneration Of Macula And Posterior Pole

  • Degeneration Of Macula And Posterior Pole Of Retina

  • Degeneration Of Macula Or Posterior Pole

  • Macular Degeneration Nos

  • Degenerative Disorder Of Macula

  • Drusen Macular Degeneration

  • Posterior Pole Macular Degeneration Of Eye

  • Macular Eye Degeneration

  • Macular Degeneration Of Retina, Unspecified

  • Pseudohole Degeneration Of Macula Of Retina
Malaria

  • Malaria, Susceptibility To

  • Malaria, Resistance To

  • Malaria, Cerebral

  • Cerebral Malaria

  • Malaria, Severe, Susceptibility To

  • Malaria, Severe, Resistance To

  • Malaria, Cerebral, Susceptibility To

  • Induced Malaria

  • Malaria, Vivax, Protection Against

  • Malaria, Severe

  • Malaria, Cerebral, Reduced Risk Of

  • Malaria, Protection Against

  • Resistance To Malaria Due To G6pd Deficiency

  • Malaria Due To G6pd Deficiency

  • Malarial Encephalitis

  • CM

  • Malaria Cerebral

  • Susceptibility To Malaria

  • Acute Pernicious Fever

  • Aestivo-Autumnal Fever

  • Aestivo Autumnal Malaria

  • Chagres Fever

  • Continued Malaria Fever

  • Estivo-Autumnal Fever

  • Estivo-Autumnal Malaria

  • Estivo-Autumnal Malarial Fever

  • Falciparum Fever

  • Malignant Tertian Fever

  • Malignant Tertian Malaria

  • Pernicious Intermittent Fever

  • Pernicious Malaria

  • Quotidian Malaria

  • Subtertian Fever

  • Subtertian Malaria Fever

  • Subtertian Malignant Tertian Malaria

  • Tropical Malaria

  • Algid Malaria

  • Bilious Haemoglobinuric Fever

  • Black Water Fever

  • Blackwater Fever

  • Malarial Blackwater Fever

  • Severe Malarial Falciparum

  • West African Fever

  • Malarial Haematinuria

  • Haemoglobinuric Fever

  • Haemoglobinuric Malaria

  • Severe Plasmodium Falciparum Malaria

  • Malarial Haemoglobinuria

  • Malarial Haematuria

  • Falciparum Malaria [Malignant Tertian]

  • Malaria Tropica

  • Malarial Shock

  • Chagres Virus Disease

  • Malignant Malaria

  • Mtm - [Malignant Tertian Malaria]

  • Tm -[Malignant Tertian Malaria]

  • Panama Fever

  • St - [Subtertian Malaria]

  • Malarial Quotidian

  • Benign Tertian Malaria

  • Tertian Ague

  • Vivax Fever

  • Plasmodium Vivax Malaria Nos

  • Btm - [Benign Tertian Malaria]

  • Bt - [Benign Tertian Malaria]

  • Vivax Malaria

  • Benign Tertian Vivax Malaria

  • Tertian Malaria

  • Quartan Malaria

  • Quartan Ague

  • Quartan Fever

  • Plasmodium Malariae Malaria Nos

  • Quartan Malarial

  • Malaria By Plasmodium Malariae

  • Malariae Malaria

  • Ovale Tertian Malaria

  • Plasmodium Ovale Fever

  • Malaria Fever By Plasmodium Ovale

  • Ovale Malaria

  • Malaria By Plasmodium Ovale

  • Malarial Ovale

  • Marsh Fever

  • Remittent Congestive Fever

  • Coastal Fever

  • Remittent Gastric Fever

  • Miasmatic Fever

  • Congestive Remittent Fever

  • Intermittent Fever

  • Jungle Fever

  • Paludism

  • Cameroon Fever

  • Ague

  • Corsican Fever

  • Intermittent Bilious Fever

  • Disease Due To Plasmodiidae

  • Malarial Fever

  • Plasmodiosis

  • Remittent Fever

  • Roman Fever

  • Malaria Fever Nos

  • Malaria Nos

  • Paludal Fever

  • Clinically Diagnosed Malaria

  • Clinically Diagnosed Malaria Without Parasitological Confirmation

  • Congestive Fever

  • Malarial Cachexia

  • Marsh Cachexia

  • Paludal Cachexia

  • Recurrent Malaria

  • Remittent Malaria
Cutis Laxa, Autosomal Dominant 3

  • ADCL3

  • Autosomal Dominant Cutis Laxa 3

  • Cutis Laxa, Autosomal Dominant, 3
Lipoprotein Quantitative Trait Locus

  • Coronary Artery Disease

  • Coronary Artery Disease, Susceptibility To

  • Coronary Artery Anomaly

  • Myocardial Ischemia

  • Congenital Anomaly Of Coronary Artery

  • Coronary Arteriosclerosis

  • Coronary Disease

  • Coronary Heart Disease

  • Coronary Artery Disorder

  • LPAQTL

  • Lpa Deficiency, Congenital

  • Coronary Artery Abnormality

  • Coronary Artery Anomaly, Congenital

  • Chd

  • Coronary Syndrome

  • Congenital Malformations Of Coronary Vessels

  • Malformation Of Coronary Vessels

  • Congenital Coronary Artery Anomaly

  • Congenital Coronary Artery Deformity

  • Congenital Coronary Artery Disorder

  • Abnormal Coronary Artery

  • Congenital Coronary Artery Malposition

  • Congenital Coronary Disease

  • Congenital Anomaly Of Coronary Arteries
Retinal Vasculitis
Human Immunodeficiency Virus Type 1

  • Aids

  • Hiv/Aids

  • Aids, Delayed/Rapid Progression To

  • Hiv-1, Susceptibility To

  • Hiv-1 Viremia, Susceptibility To

  • Human Immunodeficiency Virus Type 1, Susceptibility To

  • Hiv-1

  • Aids, Slow Progression To

  • Rapid Progression To Aids From Hiv1 Infection

  • Hiv1 Infection, Resistance To

  • Hiv1 Infection

  • Hiv-1 Viremia

  • Aids, Resistance To

  • Aids, Rapid Progression To

  • Hiv/Aids, Susceptibility To

  • Hiv-1, Resistance To

  • Hiv1, Resistance To

  • Hiv1

  • Hiv-1 Disease, Delayed Progression Of

  • Hiv-1 Disease, Rapid Progression Of

  • Hiv Infection, Resistance To

  • Hiv Type 1, Susceptibility To

  • Hiv Type 1

  • Hiv-1 Infection

  • Human Immunodeficiency Virus I Infection

  • Acquired Immunodeficiency Syndrome

  • Hiv-Infection/Aids
Nervous System Disease

  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder
Stroke, Ischemic

  • Cerebral Infarction

  • Stroke

  • Ischemic Stroke

  • Cerebrovascular Accident

  • Cerebral Infarction, Susceptibility To

  • Stroke, Ischemic, Susceptibility To

  • Cerebral Infarct

  • Ischemic Stroke, Susceptibility To

  • Stroke, Susceptibility To

  • Cva - Cerebral Infarction

  • ISCHSTR

  • Ischemic Cerebrovascular Accident
Systemic Lupus Erythematosus

  • Lupus Nephritis

  • SLE

  • Disseminated Lupus Erythematosus

  • Systemic Lupus Erythematosus, Susceptibility To

  • Lupus Erythematosus, Systemic

  • Lupus Nephritis, Susceptibility To

  • Libman-Sacks Disease

  • Systemic Lupus Erythematosus Susceptibility To

  • Sle - Lupus Erythematosus, Systemic

  • Le Syndrome

  • Lupus

  • Lupus Erythematosus Systemic

  • Lupus Erythematosus, Systemic, Susceptibility To

  • Lupus Vulgaris

  • Lupus Erythematosus, Discoid

  • Lupus Erythematosus

  • Systemic Lupus Erythematosus Nos

  • Sle - [Systemic Lupus Erythematosus]
Amyotrophic Lateral Sclerosis 1

  • Amyotrophic Lateral Sclerosis

  • ALS

  • Lou Gehrig Disease

  • Amyotrophic Lateral Sclerosis Type 1

  • Charcot Disease

  • ALS1

  • Amyotrophic Lateral Sclerosis, Susceptibility To

  • Fals

  • Lou Gehrig'S Disease

  • Mnd

  • Motor Neuron Disease

  • Familial Amyotrophic Lateral Sclerosis

  • Amyotrophic Lateral Sclerosis 1, Familial

  • Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

  • Motor Neuron Disease, Bulbar

  • Motor Neurone Disease

  • Amyotrophic Lateral Sclerosis With Dementia

  • Dementia With Amyotrophic Lateral Sclerosis

  • Motor Neuron Disease, Amyotrophic Lateral Sclerosis

  • Sclerosis, Lateral, Amyotrophic

  • Sclerosis, Lateral, Amyotrophic, Type 1

  • Amyotrophic Sclerosis

  • Als - [Amyotrophic Lateral Sclerosis]

  • Wasting Palsy

  • Amyotrophic Paralysis

  • Amyotrophy Lateral Sclerosis

  • Wasting Paralysis

  • Spinal Progressive Amyotrophy

  • Progressive Atrophic Paralysis
Chorioretinal Scar

  • Chorioretinal Cicatrix

  • Cicatrix Of Choroid

  • Choroid Scar

  • Macula Scar

  • Macular Scarring

  • Retinal Cicatrix

  • Retinal Scar
Macular Degeneration, Age-Related, 12

  • ARMD12

  • Age Related Macular Degeneration 12

  • Macular Degeneration, Age-Related, Type 12
Cerebrovascular Disease

  • Cerebrovascular Accident

  • Cerebrovascular Disorder

  • Cerebrovascular Disorders

  • Cva

  • Stroke
Myocardial Infarction

  • Heart Attack

  • Myocardial Infarction, Susceptibility To

  • Myocardial Infarction 1

  • Myocardial Infarction, Protection Against

  • Myocardial Infarction, Decreased Susceptibility To

  • Myocardial Infarction, Decreased

  • Myocardial Infarct

  • MCI1

  • Premature Myocardial Infarction

  • Myocardial Infarction, Susceptibility To, Type 1
Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1

  • Nasu-Hakola Disease

  • Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy

  • Plosl

  • Nhd

  • Presenile Dementia With Bone Cysts

  • Plo-Sl

  • PLOSL1

  • Dementia, Prefrontal, With Bone Cysts

  • Dementia, Progressive, With Lipomembranous Polycystic Osteodysplasia

  • Brain-Bone-Fat Disease

  • Progressive Dementia With Lipomembranous Polycystic Osteodysplasia

  • Brain-Bone-Fat Disease
Inflammatory Bowel Disease

  • Inflammatory Bowel Diseases

  • Bowel Disease, Inflammatory
Dermatitis

  • Eczema

  • Skin Inflammation

  • Inflammatory Dermatosis
Cutis Laxa, Autosomal Dominant 2

  • ADCL2

  • Autosomal Dominant Cutis Laxa 2

  • Cutis Laxa, Autosomal Dominant, 2

  • Cutis Laxa, Autosomal Dominant, Type 2
Asthma

  • Chronic Obstructive Asthma

  • Asthma, Diminished Response To Antileukotriene Treatment In

  • Bronchial Hyperreactivity

  • Asthma, Susceptibility To

  • Asthma, Bronchial

  • Asthma, Protection Against

  • Asthma, Nocturnal, Susceptibility To

  • Nocturnal Asthma

  • Asthma-Related Traits

  • Asthma-Related Traits, Susceptibility To

  • Asthma, Nocturnal

  • Chronic Obstructive Asthma With Acute Exacerbation

  • Chronic Obstructive Asthma With Status Asthmaticus

  • Exercise Induced Asthma

  • Exercise-Induced Asthma

  • Bronchial Asthma

  • Asthma, Exercise-Induced

  • Idiosyncratic Asthma

  • Unspecified Asthma With Acute Exacerbation

  • Asthma, Unspecified, With Stated Status Asthmaticus

  • Status Asthmaticus Nos

  • Acute Severe Asthma

  • Acute Severe Bronchial Asthma

  • Status Asthma

  • Status Post Asthmaticus
Human Immunodeficiency Virus Infectious Disease

  • Hiv Infections
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Rheumatoid Arthritis

  • RA

  • Arthritis, Rheumatoid

  • Rheumatoid Arthritis, Susceptibility To

  • Arthritis Or Polyarthritis, Rheumatic

  • Atrophic Arthritis

  • Rheumatism Arthritis

  • Rheumatoid Polyarthritis
Immune Deficiency Disease

  • Immunodeficiency

  • Primary Immunodeficiency Disease

  • Primary Immunodeficiency

  • Immunologic Deficiency Syndromes

  • Hypoimmunity

  • Immune Deficiency Disorder

  • Immunodeficiency Syndrome

  • Immune Disorder

  • Primary Immune Deficiency Disorder

  • Immune System Diseases

  • Human Immunodeficiency Virus Infection

  • Hiv - [Human Immunodeficiency Virus Infection]

  • Hiv Positive Nos

  • Hiv Disease

  • Acquired Immune Deficiency Syndrome-Related Complex

  • Aids-Like Syndrome

  • Aids-Related Complex Nos

  • Arc - [Aids-Related Complex]

  • Immunodeficiency Due To Human Immunodeficiency Virus Infection

  • Unspecified Human Immunodeficiency Virus Disease

  • Hiv Disease Nos

  • Human Immunodeficiency Virus Positive Nos

  • Hiv Nos

  • Deficiency Of Complement Initial Pathway

  • Deficiency Of Complement Terminal Pathway

  • Cfdd - [Complement Factor D Deficiency]

  • Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency

  • Nonfamilial Hypogammaglobulinaemia

  • Common Variable Immune Deficiency

  • Nonfamilial Agammaglobulinaemia

  • Common Variable Agammaglobulinaemia

  • Agammaglobulinaemia Nos

  • Agammaglobulinaemia Antibody Deficiency Syndrome

  • Hypogammaglobulinaemia Antibody Deficiency Syndrome

  • Acquired Agammaglobulinaemia Nos

  • Hypogammaglobulinaemia Nos

  • Hyper Igm
Neuritis

  • Peripheral Neuritis
Autism

  • Autistic Disorder

  • Autism Susceptibility 1

  • Childhood Autism

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Kanner'S Syndrome

  • Autistic
Tonsillitis

  • Chronic Tonsillitis

  • Throat Infection - Tonsillitis
Psoriasis
Macular Degeneration, Age-Related, 1

  • Macular Degeneration

  • Age-Related Macular Degeneration

  • Macular Degeneration, Age-Related

  • Age Related Macular Degeneration

  • Age Related Macular Degeneration 1

  • ARMD1

  • Maculopathy, Age-Related, 1

  • Macular Degeneration, Age-Related, Reduced Risk Of

  • Age Related Maculopathy 1

  • Age Related Maculopathies

  • Age Related Maculopathy

  • Senile Macular Degeneration

  • Senile Macular Retinal Degeneration

  • Macular Degeneration Of Retina

  • Age-Related Maculopathy

  • Amd

  • Armd

  • Age-Related Maculopathy, Susceptibility To

  • Maculopathy Age-Related

  • Macular Degeneration, Age-Related, 1, Susceptibility To

  • Maculopathy, Age-Related

  • Macular Degeneration, Age-Related, Type 1

  • Macular Degeneration, Age-Related, 2
Multiple Sclerosis

  • MS

  • Multiple Sclerosis, Susceptibility To

  • Disseminated Sclerosis

  • Multiple Sclerosis, Disease Progression, Modifier Of

  • Insular Sclerosis

  • Multiple Sclerosis Modifier Of Disease Progression

  • Multiple Sclerosis, Susceptibility To 1

  • Multiple Sclerosis, Susceptibility To, 1

  • Multiple Sclerosis 1

  • Generalized Multiple Sclerosis

  • Multiple Sclerosis Variant

  • Multiple Sclerosis Susceptibility To

  • Cerebrospinal Sclerosis

  • Generalised Multiple Sclerosis

  • Ms - [Multiple Sclerosis]

  • Disseminated Cerebrospinal Sclerosis

  • Disseminated Multiple Sclerosis

  • Disseminated Nervous System Myelosclerosis

  • Multiple Cerebrospinal Sclerosis

  • Multiple Combined Sclerosis

  • Multiple Sclerosis Generalised

  • Disseminated Brain Sclerosis

  • Disseminated Spinal Sclerosis

  • Insular Brain Sclerosis

  • Miliary Brain Sclerosis

  • Multiple Combined Sclerosis Of Spinal Cord

  • Multiple Ascending Sclerosis

  • Multiple Brain Sclerosis

  • Multiple Sclerosis Of Brain Stem

  • Multiple Sclerosis Of The Brain Stem

  • Multiple Sclerosis Of Cord

  • Sclérose En Plaques

  • Plaque Sclerosis

  • Multiple Sclerosis Of The Spinal Cord
Heart Disease

  • Heart Failure

  • Congenital Heart Disease

  • Heart Diseases

  • Congenital Heart Defects

  • Congenital Heart Defect

  • Congenital Anomaly Of Heart

  • Heart Defect

  • Heart Malformation

  • Heart-Congenital Defect

  • Congenital Heart Disorder

  • Heart Defects Congenital

  • Heart Defects, Congenital

  • Heart Defects

  • Heart Disease, Congenital

  • Disease, Heart, Congenital

  • Congestive Heart Failure
Dermatitis, Atopic

  • Atopic Dermatitis

  • Atopic Eczema

  • Dermatitis, Atopic, Susceptibility To, 1

  • Atod

  • Eczema, Atopic

  • Dermatitis, Atopic 1

  • Allergic Dermatitis

  • Atopic Neurodermatitis

  • Besnier'S Prurigo

  • Dermatitis, Atopic, 1

  • Dermatitis Atopic

  • Eczema

  • Besnier Prurigo
Leukoencephalopathy, Hereditary Diffuse, With Spheroids 1

  • Adult-Onset Leukoencephalopathy With Axonal Spheroids And Pigmented Glia

  • Hereditary Diffuse Leukoencephalopathy With Spheroids

  • Alsp

  • Gpsc

  • Subcortical Gliosis Of Neumann

  • Autosomal Dominant Leukoencephalopathy With Neuroaxonal Spheroids

  • Hdls

  • HDLS1

  • Leukoencephalopathy, Adult-Onset, With Axonal Spheroids And Pigmented Glia

  • Gliosis, Familial Progressive Subcortical

  • Leukoencephalopathy, Diffuse Hereditary, With Spheroids 1

  • Leukoencephalopathy, Diffuse Hereditary, With Spheroids

  • Pold

  • Pigmentary Orthochromatic Leukodystrophy

  • Hereditary Diffuse Leukoencephalopathy With Axonal Spheroids And Pigmented Glia

  • Familial Progressive Subcortical Gliosis

  • Leukoencephalopathy With Neuroaxonal Spheroids, Autosomal Dominant

  • Dementia, Familial, Neumann Type

  • Adult-Onset Leukodystrophy With Neuroaxonal Spheroids

  • Hereditary Diffuse Leukoencephalopathy With Axonal Spheroids

  • Neuroaxonal Leukodystrophy

  • Fpsg

  • Familial Dementia, Neumann Type

  • Familial Dementia Neumann Type

  • Leukoencephalopathy, Diffuse Hereditary, With Spheroid
Pneumoconiosis

  • Pneumoconioses

  • Silicosis Nos

  • Complicated Silicosis

  • Fibrosis Of Lung With Silicosis

  • Nodular Silicosis

  • Pneumoconiosis Due To Silica

  • Silicotic Fibrosis Of Lung

  • Simple Silicosis

  • Silicatosis

  • Silicotic Lung Fibrosis

  • Pneumoconiosis Due To Talc

  • Pulmonary Talcosis

  • Talc Lung Disease

  • Talc Pneumoconiosis

  • Talc Workers' Pneumoconiosis

  • Talcosis

  • Fibrosis Of Lung Due To Talc

  • Asbestos Pneumoconiosis

  • Amianthosis

  • Asbestosis

  • Lung Fibrosis With Asbestosis

  • Pulmonary Asbestosis
Thrombocytopenia

  • Low Platelet Count

  • Low Platelets

  • Decreased Platelets

  • Platelet Dysfunction Nos
Coronary Heart Disease 1

  • Coronary Heart Disease

  • Coronary Heart Disease, Susceptibility To, 1

  • Chds1

  • Coronary Heart Disease, Susceptibility To

  • CHD

  • Heart, Coronary, Disease, Susceptibility To, Type 1

  • Coronary Arteriosclerosis

  • Coronary Artery Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9928 Alirocumab 97.00% Unkown

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-13848 Rugocrixan 99.54% Phase 2
HY-107456 E6130 98.0% Phase 1
HY-175746 AZD0233 Antagonist 98.66% Phase 1

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123918 JMS-17-2 99.18% Unkown
HY-123918A JMS-17-2 hydrochloride / Unkown
HY-168975 Fosrugocrixan Antagonist / Unkown
HY-179653 CX3CR1-IN-1 Inhibitor / Unkown
HY-181016 CX3CR1-IN-2 Inhibitor / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P9928A Alirocumab (anti-PCSK9) 98.24% Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CX3CR1 VGNC VGNC:39746
Macaca mulatta CX3CR1 VGNC VGNC:71571
Felis catus CX3CR1 VGNC VGNC:82469
Rattus norvegicus CX3CR1 RGD RGD:620137
Mus musculus CX3CR1 MGD MGI:1333815
Bos taurus CX3CR1 VGNC VGNC:27845
Others CX3CR1 NCBI