Ldhc - lactate dehydrogenase C Gene

Also Known as Ldh3; Ldh-3; Ldh-x; Ldhc4; LDH-C4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16833

Summary

Enables L-lactate dehydrogenase activity. Acts upstream of or within ATP biosynthetic process; flagellated sperm motility; and lactate metabolic process. Located in cytoplasm and motile cilium. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human LDHC (Lactate Dehydrogenase C). [provided by Alliance of Genome Resources, Apr 2022]

Ldhc Products (3)

mRNA Protein Name
NM_001368361.1 NP_001355290.1 L-lactate dehydrogenase C chain
NM_001368362.1 NP_001355291.1 L-lactate dehydrogenase C chain
NM_013580.4 NP_038608.1 L-lactate dehydrogenase C chain

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-lactate dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
18367675 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23055941 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ATP biosynthetic process IMP
IMP: Inferred from mutant phenotype
18367675 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
18367675 MGI
acts upstream of or within lactate biosynthetic process from pyruvate IDA
IDA: Inferred from direct assay
18367675 MGI
acts upstream of or within lactate metabolic process IDA
IDA: Inferred from direct assay
18367675 MGI
involved in pyruvate catabolic process IMP
IMP: Inferred from mutant phenotype
21565994 MGI
acts upstream of or within pyruvate metabolic process IDA
IDA: Inferred from direct assay
18367675 MGI
Cellular Component GO Annotation Evidence References Source
located in cilium IDA
IDA: Inferred from direct assay
16687649 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
18367675 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
16582413 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
18367675 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

L-lactate dehydrogenase C chain

  • LDH testis subunit

  • LDH-C

  • lactate dehydrogenase 3, C chain, sperm specific

  • lactate dehydrogenase-X

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100742A (R)-GNE-140 Inhibitor 99.77% Unkown
HY-RS07573 LDHC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100742AR (R)-GNE-140 (Standard) Inhibitor / Unkown
HY-RS21363 Ldhc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27882 Ldhc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ldhc NCBI NCBI:3948