AFP - alpha fetoprotein Gene

Also Known as AFPD; FETA; HPAFP

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 174

About AFP

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:73,436,221-73,456,174 (from NCBI)

This gene has 7 transcripts (splice variants), 142 orthologues, 3 paralogues and is associated with 4 phenotypes. Biased expression in kidney (RPKM 1.8) and liver (RPKM 1.6).

Summary

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric Cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]

AFP Products (2)

mRNA	Protein	Name
NM_001134.3	NP_001125.1	alpha-fetoprotein isoform 1 precursor
NM_001354717.2	NP_001341646.2	alpha-fetoprotein isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	26808496	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AFP Protein Structure

Serum_albumin

0
100
200
300
400
500
609 a.a.

Protein Preferred Names	Protein Names
alpha-fetoprotein	alpha-1-fetoprotein

Recombinant AFP Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7463	Alpha-Fetoprotein Protein, Human (HEK293, His)	P02771 (T20-V609)	≥ 95%, as determined by reducing SDS-PAGE.

AFP Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81077	AFP Antibody (YA914)	WB, ELISA, IHC-P, IHC-F, ICC/IF	Human, Rat,
HY-P81078	AFP Antibody (YA915)	WB, IHC-P, ICC/IF, FC	Human
HY-P83929	AFP Antibody (YA3626)	WB, ELISA	Human
HY-P83929A	AFP Antibody (YA3626)(PBS only)	WB, ELISA	Human
HY-P83930	AFP Antibody (YA3627)	IHC-P, FC, ELISA	Human
HY-P83930A	AFP Antibody (YA3627)(PBS only)	IHC-P, FC, ELISA	Human
HY-P85793	AFP Antibody (YA5485)	WB, ICC/IF, ELISA	Human, Mouse, Rat
HY-P86117	AFP Antibody (YA5809)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Alpha-Fetoprotein Deficiency	AFPD Congenital Deficiency In Alpha-Fetoprotein
Alpha-Fetoprotein, Hereditary Persistence Of	HPAFP Hereditary Persistence Of Alpha-Fetoprotein Alpha-Fetoprotein, Hereditary Persistence
Teratoma	Teratomas
Endodermal Sinus Tumor	Yolk Sac Tumor Endodermal Sinus Tumour Hepatoid Yolk Sac Tumour Infantile Embryonal Carcinoma Yolk Sac Neoplasm Yolk Sac Tumour
Germinoma
Germ Cell Cancer	Malignant Germ Cell Tumor Neoplasms, Germ Cell And Embryonal Germ Cell Neoplasm Germ Cell Tumour Malignant Tumor Of The Germ Cell Neoplasms Germ Cell Malignant Germ Cell Neoplasm
Seminoma	Seminoma, Pure
Sertoli-Leydig Cell Tumor	Sertoli-Leydig Cell Tumors Androblastoma Of Ovary Arrhenoblastoma Arrhenoblastoma Of Ovary Sertoli-Leydig Cell Tumor Of The Ovary Sertoli-Leydig Cell Tumor Of Intermediate Differentiation Sertoli-Leydig Cell Tumor Of Ovary
Testicular Yolk Sac Tumor	Testicular Yolk Sac Neoplasm Endodermal-Sinus Tumor Orchidoblastoma Yolk Sac Tumor
Benign Teratoma	Dermoid Cyst Cystic Dermoid Choristoma Dermoid Choristoma Mature Cystic Teratoma Dermoid Tumour Teratoma, Benign Dermoid Cyst Of Ovary
Embryonal Carcinoma	Embryonal Neoplasm Embryonal Cancer Primary Extragonadal Embryonal Carcinoma Embryo Neoplasm Carcinoma Embryonal Cancer Embryonal Carcinoma, Embryonal Extragonadal Embryonal Carcinoma Cancer, Embryonal
Hydrocele	Testicular Hydrocele
Extragonadal Germ Cell Cancer	Extragonadal Germ Cell Tumor Extragonadal Germ Cell Malignant Tumor Neoplasm Of Extragonadal Germ Cell Tumor Of Extragonadal Germ Cell
Liver Cirrhosis	Cirrhosis Cirrhosis Of Liver CIRRH Cryptogenic Cirrhosis Cirrhosis, Cryptogenic Cirrhosis Nos
Viral Hepatitis	Animal Viral Hepatitis Hepatitis, Viral, Animal Human Viral Hepatitis Viral Hepatitis With Hepatic Coma
Testicular Cancer	Testis Cancer Testicular Carcinoma Testicular Neoplasms Malignant Neoplasm Of Testis Childhood Neoplasm Of The Testis Neoplasm Of Testis Pediatric Testicular Neoplasm Testicular Tumor Testis Neoplasm Testicular Tumors Testicular Neoplasm Testicular Malignant Germ Cell Tumor Childhood Testicular Neoplasm Carcinoma Of The Testis Cancer Of Testis Malignant Neoplasm Of Testis, Nos Malignant Neoplasm Of Testis, Unspecified Malignant Tumour Of Testis Testicle Cancer Primary Malignant Neoplasm Of Testis
Ovarian Mixed Germ Cell Neoplasm	Mixed Germ Cell Tumor Of Ovary Ovarian Mixed Germ Cell Tumor
Orofaciodigital Syndrome Viii	Edwards Syndrome Trisomy 18 Complete Trisomy 18 Syndrome OFD8 Orofaciodigital Syndrome 8 Trisomy 18 Syndrome Oral-Facial-Digital Syndrome With Hypoplastic Epiglottis E3 Trisomy Oral-Facial-Digital Syndrome Type 8 Orofaciodigital Syndrome Type 8 Ofds Viii Oral-Facial-Digital Syndrome, Type Viii Ofd Syndrome 8 Ofds 8 Oral Facial Digital Syndrome 8 Oral Facial Digital Syndrome Type 8 18 Trisomy Chromosome 18 Trisomy Trisomy 16-18 Trisomy E Trisomy E Syndrome Chromosome 18 Duplication Oral-Facial-Digital Syndrome, Edwards Type Orofaciodigital Syndrome, Edwards Type Chromosome 18, Trisomy Cleft Lip/Palate With Abnormal Thumbs And Microcephaly Trisomy 18 Chromosome Abnormal Autosomes 18
Liver Disease	Liver Failure Liver Diseases Abnormality Of The Liver Liver Dysfunction Disorder Of Liver Hepatic Disorder Hepatic Disease Disease Of Bilirubin Metabolism Disorder Of Bilirubin Metabolism Liver Decompensation Liver Function Failure Hepatic Failure Nos Liver Failure Nos End Stage Liver Disease Decompensated Liver Failure Decompensation Of Liver Function Hepatic Decompensation Hepatic Insufficiency Liver Cell Necrosis With Hepatic Failure Liver Insufficiency Decompensated Liver Disease End Stage Liver Failure Liver Necrosis With Hepatic Failure
Chromosomal Disease	Chromosomal Disorders Congenital Chromosomal Disease
Neural Tube Defects	Spina Bifida Neural Tube Defect NTD Neural Tube Defects, Susceptibility To Spinal Dysraphism Spina Bifida, Susceptibility To Rachischisis Cleft Spine Open Spine Hydrocele Spinalis Neural Tube Defect Nos Sb - [Spina Bifida] Spinal Hernia Nos Spinal Fissure Nos
Malignant Teratoma	Immature Teratoma Malignant Extragonadal Teratoma Primary Malignant Extragonadal Teratoma Teratoma, Malignant, Nos Teratoma, Malignant Immature Extragonadal Teratoma
Tyrosinemia, Type I	Tyrosinemia Type I Hepatorenal Tyrosinemia Fumarylacetoacetase Deficiency Fah Deficiency TYRSN1 Fumarylacetoacetate Hydrolase Deficiency Tyrosinemia Type 1 Tyrosinemia 1 Fumarylacetoacetase
Anencephaly	Aprosencephaly Anencephalus Congenital Absence Of Brain Absence Of A Large Part Of The Brain And The Skull Anencephalia Anencephalic Monster Brain Absence Brain Agenesis Brain Aplasia Absent Brain Anencephalic Congenital Absence Of Cerebrum Congenital Hemicrania Incomplete Anencephaly
Mature Teratoma	Dermoid Cyst Benign Teratoma
Hepatitis B	Chronic Hepatitis B Hepatitis B Infection Serum Hepatitis HBV Hepatitis B Chronic Hbv, Susceptibility To Hepatitis B, Chronic Chronic Hepatitis B Without Delta Agent Chronic Hbv - [Hepatitis B Virus] Infection Hepatitis B Nos Chronic Type B Viral Hepatitis Hep B Nos
Mixed Germ Cell Cancer	Mixed Germ Cell Tumor Mixed Germ Cell Neoplasm Mixed Germ Cell Tumour Mixed Teratoma And Seminoma
Oligohydramnios	Oligohydramnios - Delivered Antepartum Oligohydramnios Delivered Oligohydramnios Oligohydramnios, Antepartum Condition Or Complication Deficient Liquor Oligohydramnios, Unspecified Trimester Reduced Liquor Volume
Hepatitis	Chronic Hepatitis Chronic Persistent Hepatitis Acute Hepatitis Hepatitis, Chronic Acute And Subacute Liver Necrosis Acute/Subac. Necrosis Of Liver Animal Hepatitis Hepatitis Chronic Hepatitis A Hepatitis, Animal Hepatitis Due To Toxoplasmosis Hepatitis In Toxoplasmosis Toxoplasmal Hepatitis Chronic Hepatitis, Unspecified Chronic Active Hepatitis Nec Other Specified Chronic Hepatitis Chronic Persistent Hepatitis Nec Chronic Lobular Hepatitis Nec
Portal Vein Thrombosis	Phlebitis Of Portal Vein Deep Vein Thrombosis Of Portal Vein Portal Thrombosis Pvt - [Portal Vein Thrombosis] Portal Venous Thrombosis Portal Venous Embolism Portal Venous Obstruction Portal Venous Block Portal Vein Embolism Portal Vein Block Portal Obstruction Portal Embolism Portal Block Hepatic Portal Vein Obstruction Occlusion Of Hepatic Portal Vein Portal Vein Obstruction
Bile Duct Cancer	Bile Duct Carcinoma Extrahepatic Bile Duct Carcinoma Carcinoma Of Extrahepatic Bile Duct Extrahepatic Bile Duct Cancer Bile Duct Neoplasms Bile Duct Tumor Ca Extrahepatic Bile Ducts Malignant Neoplasm Of The Extrahepatic Bile Duct Bile Duct Extrahepatic Carcinoma Malignant Tumor Of Extrahepatic Bile Duct
Tyrosinemia	Hypertyrosinemia Tyrosinemias Hereditary Tyrosinemia Hypertyrosinaemia Tyrosinaemia Hereditary Hypertyrosinemia
Cystic Teratoma	Dermoid Cyst Benign Teratoma
Ovarian Cyst	Ovarian Cysts
Placenta Disease	Placenta Diseases Placenta Disorder Pregnancy Complications Placenta Disorders
Ovarian Primitive Germ Cell Tumor
Ovarian Endodermal Sinus Tumor	Endodermal Sinus Tumor Of Ovary Ovarian Yolk Sac Tumor Endodermal Sinus Tumour Of Ovary Ovarian Endodermal Sinus Tumour Ovarian Yolk Sac Tumour
Mediastinal Cancer	Mediastinal Neoplasms Mediastinal Tumor Mediastinum Cancer Neoplasm Of Mediastinum Tumour Of Mediastinum Malignant Tumor Of Mediastinum
Gastric Teratoma	Teratoma Of Stomach
Hepatitis C	Chronic Hepatitis C Hepatitis C Infection Hepatitis Nona Nonb Nanbh Viral Hepatitis C Hepatitis C Chronic Hepatitis C, Chronic Chronic Type C Viral Hepatitis Chronic Hcv - [Hepatitis C Virus] Infection Hepatitis C Nos Hepatitis C Infection Nos Hepatitis C-Related Cirrhosis Type C Viral Hepatitis Hep C Nos
Hepatoblastoma
Chorioangioma	Placental Hemangioma
Intermediate Malignant Teratoma	Malignant Teratoma, Intermediate Intermediate Immature Teratoma
Adult Teratoma
Choriocarcinoma Of The Testis	Testicular Choriocarcinoma
Vaginal Yolk Sac Tumor	Vaginal Endodermal Sinus Neoplasm Vaginal Yolk Sac Neoplasm
Hepatoid Adenocarcinoma
Acinar Cell Carcinoma	Acinic Cell Carcinoma Acinic Cell Tumor Carcinoma Acinar Cell Carcinoma, Acinar Cell Acinar Cell Tumor
Ovarian Embryonal Carcinoma	Embryonal Carcinoma Of Ovary Embryonal Carcinoma Of The Ovary
Dysgerminoma
Mature Gastric Teratoma	Mature Teratoma Of Stomach
Extragonadal Nonseminomatous Germ Cell Tumor	Primary Malignant Extragonadal Nonseminoma Malignant Extragonadal Non-Seminomatous Germ Cell Tumor
Dermoid Cyst Of Ovary	Dermoid Cyst Ovarian Dermoid Cyst Teratoma, Ovarian
Liver Inflammatory Pseudotumor	Inflammatory Pseudotumor Of The Liver Liver Inflammatory Myofibroblastic Tumor
Childhood Testicular Germ Cell Tumor	Paediatric Testicular Germ Cell Neoplasm Paediatric Testicular Germ Cell Tumour Pediatric Testicular Germ Cell Neoplasm Pediatric Testicular Germ Cell Tumor Testicular Germ Cell Tumor, Pediatric
Adenomatoid Tumor	Adenomatoid Tumour Benign Localised Epithelial Mesothelioma Benign Localized Epithelial Mesothelioma
Vitamin K Deficiency Bleeding	Vitamin K Deficiency Deficiency Of Vitamin K Vitamin K Vitamin K Deficiency Hemorrhagic Disease
Placenta Accreta
Tubular Adenocarcinoma	Tubular Carcinoma Adenocarcinoma Tubular Adenocarcinoma, Tubular
Down Syndrome	Trisomy 21 Complete Trisomy 21 Syndrome Down'S Syndrome Trisomy 21 Syndrome Down'S Syndrome - Trisomy 21 Downs Syndrome G Trisomy 47,Xx,+21 47,Xy,+21 Trisomy G Down Syndrome, Susceptibility To Chromosome 21 Trisomy Trisomy 21 Nos Abnormal Autosomes 21
Pineal Region Teratoma	Teratoma Of Pineal Area
Premature Menopause	Primary Ovarian Insufficiency Premature Ovarian Failure Hypergonadotropic Hypogonadism Premature Ovarian Insufficiency Menopause - Premature Menopause Praecox Menopause Premature Menopause, Premature Female Hypergonadotropic Hypogonadism Hypergonadotrophic Ovarian Failure Primary Female Hypogonadism Pof - [Premature Ovarian Failure] Ovarian Failure Ovarian Secretion Suppression Ovary Hyposecretion Ovary Secretion Deficiency Premature Menopause Nos
Sertoli Cell Tumor	Tubular Androblastoma
Hepatic Vascular Disease	Vascular Disorder Of Liver
Vein Disease	Disorder Of Vein
Liver Lipoma	Hepatic Lipoma Lipoma Of The Liver
Mixed Type Rhabdomyosarcoma	Mixed Embryonal Rhabdomyosarcoma And Alveolar Rhabdomyosarcoma
Brain Germinoma	Intracranial Germinoma Germinoma Of The Brain
Pancreatoblastoma
Hepatic Angiomyolipoma
Extragonadal Seminoma	Primary Extragonadal Seminoma
Leydig Cell Tumor	Leydig Cell Neoplasm Tumor, Leydig Cell Leydig Cell Tumor, Benign
Hepatitis A	Viral Hepatitis A Viral Hepatitis, Type A
Mixed Hepatoblastoma	Mixed Epithelial And Mesenchymal Hepatoblastoma
Dysgerminoma Of Ovary	Ovarian Dysgerminoma Malignant Dysgerminomatous Germ Cell Tumour Of Ovary Dysgerminoma, Unspecified Site, Female
Classic Congenital Mesoblastic Nephroma
Fallopian Tube Cystadenofibroma
Hepatic Osteogenic Sarcoma	Osteosarcoma Of Liver Liver Extraskeletal Osteosarcoma
Malignant Pineal Area Germ Cell Neoplasm	Pineal Germ Cell Tumor Malignant Pineal Parenchymal Germ Cell Tumor Pineal Region Germ Cell Tumor Pineal Cell Tumor Pineal Cell Tumour Pineal Region Germinoma Malignant Pineal Region Germ Cell Tumor Pineal Germinoma
Bile Duct Cystadenocarcinoma	Biliary Cystadenocarcinoma Intrahepatic Bile Duct Cystadenocarcinoma Intrahepatic Bile Duct Mucinous Cystic Neoplasm With An Associated Invasive Carcinoma
Omphalocele	Omphalocoele Congenital Omphalocele Exomphalos Exumbilication
Spina Bifida Aperta	Open Spina Bifida Spina Bifida Without Hydrocephalus Spina Bifida Manifesta Spina Bifida Aperta With Tethered Spinal Cord
Alcoholic Liver Cirrhosis	Alcoholic Cirrhosis Portal Cirrhosis Alcoholic Cirrhosis Of Liver Liver Cirrhosis, Alcoholic Laennec'S Cirrhosis Laennec'S Cirrhosis, Alcoholic Alcohol Cirrhosis Alcoholic Laennec Cirrhosis Alcoholic Cirrhosis Nos Etoh Cirrhosis Alcohol Hepatic Cirrhosis Alcohol Liver Cirrhosis Laennec Cirrhosis
Fibrolamellar Carcinoma	Fibrolamellar Hepatocellular Carcinoma Fhcc Fibrolamellar Hepatocarcinoma Hepatocellular Carcinoma, Fibrolamellar Oncocytic Hepatocellular Tumor Eosinophilic Glassy Cell Hepatoma Eosinophilic Hepatocellular Carcinoma With Lamellar Fibrosis Fl-Hcc Fibrolamellar Oncocytic Hepatoma Hepatocellular Carcinoma With Increased Stromal Fibrosis Polygonal Cell Hepatocellular Carcinoma With Fibrous Stroma
Pancreatic Endocrine Carcinoma	Carcinoma Of Endocrine Pancreas Islet Cell Carcinoma Malignant Neoplasm Of Islets Of Langerhans Pancreatic Neuroendocrine Carcinoma Carcinoma Islet Cell Carcinoma, Islet Cell
Ectopic Pregnancy	Eccyesis Pregnancy Ectopic Pregnancy, Ectopic Ectopic Pregnancies Extrauterine Gestation Or Pregnancy Extrauterine Pregnancy Ep - [Ectopic Pregnancy] Ectopic Mole Aborted Ectopic Pregnancy Ruptured Ectopic Pregnancy
Cystic Lymphangioma	Cystic Hygroma Cavernous Lymphangioma Macrocystic Lymphatic Malformation Cavernous Lymphatic Malformation Macrocystic Lymphangioma Lymphangioma, Cystic
Epididymo-Orchitis
Testicular Malignant Germ Cell Cancer	Malignant Germ Cell Tumor Of Testis
Cystadenoma	Cystoma Craniopharyngioma
Liver Sarcoma	Hepatic Sarcoma Sarcoma Of Liver
Scrotum Neoplasm	Malignant Tumour Of Scrotum Malignant Scrotal Neoplasm Malignant Tumor Of Scrotum Neoplasm Of Scrotum Scrotal Ca Scrotal Tumor Scrotum Cancer Cancer Of Scrotum Malignant Neoplasm Of Scrotum Scrotal Cancer Malignant Scrotal Tumour Malignant Neoplasm Of Skin Of Scrotum Primary Malignant Neoplasm Of Scrotum
Sclerosing Hepatic Carcinoma	Sclerosing Hepatocellular Carcinoma
Liver Lymphoma	Lymphoma Of Liver
Hematocele Of Tunica Vaginalis Testis	Hematocele Male Hematocele
Esophageal Varix	Esophageal Varices Bleeding Esophageal Varices Bleeding Oesophageal Varices Esophageal Varices In Disease Classified Elsewhere, With Bleeding Esophageal Varices With Bleeding Esophageal Varices With Bleeding In Disease Ec Esophageal Varices Without Bleeding Esophageal Varices Without Mention Of Bleeding
Ovarian Benign Neoplasm	Benign Ovarian Neoplasm
Ovarian Germ Cell Cancer	Ovarian Germ Cell Tumor Malignant Germ Cell Tumor Of Ovary Germ Cell Neoplasm Of Ovary Germ Cell Tumor Of Ovary Mogct Malignant Ovarian Germ Cell Tumor Malignant Ovarian Germ Cell Neoplasm
Lipoma Of Spermatic Cord	Spermatic Cord Lipoma
Paratesticular Lipoma
Alpha-1-Antitrypsin Deficiency	Alpha 1-Antitrypsin Deficiency Alpha-1 Antitrypsin Deficiency Aat Deficiency Aatd A1ATD Emphysema Due To Aat Deficiency A1at Deficiency Emphysema-Cirrhosis, Due To Aat Deficiency Hemorrhagic Diathesis Due To Antithrombin Pittsburgh Alpha-1 Antiprotease Deficiency Alpha 1 Antitrypsin Deficiency Aat Alpha-1 Protease Inhibitor Deficiency Alpha-1 Related Emphysema Genetic Emphysema Hereditary Pulmonary Emphysema Inherited Emphysema Alpha-1-Proteinase Inhibitor Deficiency Alpha1-Antitrypsin Deficiency Alpha-1-Antitrypsin Deficiency, Autosomal Recessive Emphysema, Hereditary Pulmonary Aatd - [Alpha-1-Antitrypsin] Deficiency
Bile Duct Cysts	Choledochal Cyst Choledochal Cysts Choledochocele Biliary Cyst Congenital Choledochal Cyst Bile Duct Cyst Congenital Cystic Dilatation Of The Biliary Tract Congenital Bile Duct Dilatation
Hepatocellular Clear Cell Carcinoma	Clear Cell Carcinoma Of The Liver Cells Hepatocellular Carcinoma, Clear Cell Type Clear Cell Hepatocellular Carcinoma
Ovarian Solid Teratoma
Placental Insufficiency	Uteroplacental Vascular Insufficiency
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Nephrotic Syndrome, Type 1	Finnish Congenital Nephrosis NPHS1 Cnf Finnish Congenital Nephrotic Syndrome Nephrotic Syndrome Type 1 Nephrosis, Congenital Congenital Nephrotic Syndrome Nephrotic Syndrome, Congenital Congenital Nephrotic Syndrome Finnish Type Congenital Nephrotic Syndrome 1 Nephrosis 1, Congenital, Finnish Type Congenital Nephrotic Syndrome, Finnish Type Nephrotic Syndrome 1 Congenital Nephrotic Syndrome Of The Finnish Type
Chromosomal Triplication	Trisomy
Hepatocellular Adenoma	Adenoma Hepatocellular
Ovarian Cystic Teratoma
Gallbladder Cancer	Gallbladder Carcinoma Gallbladder Neoplasm Malignant Neoplasm Of Gallbladder Malignant Tumour Of Gallbladder Gallbladder Ca Localized Malignant Gallbladder Neoplasm Malignant Tumor Of The Gallbladder Tumor Of The Gallbladder Cancer Of The Gallbladder Carcinoma Gallbladder Carcinoma Of Gallbladder Gallbladder Neoplasms Malignant Neoplasm Of Gallbladder Localized Cancer Of Gallbladder Primary Malignant Neoplasm Of Gallbladder
Parovarian Cyst	Cyst, Fimbrial Embryonic Fimbrial Cyst
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Middle Ear Adenocarcinoma	Adenocarcinoma Of Middle Ear Adenocarcinoma Of The Middle Ear
Patau Syndrome	Trisomy 13 Complete Trisomy 13 Syndrome Trisomy 13 Syndrome D1 Trisomy Patau'S Syndrome Complete Trisomy 13 Chromosome 13, Trisomy 13 Complete D Trisomy Syndrome Bartholin-Patau Syndrome Chromosome 13 Duplication D1 Trisomy Syndrome D>1< Trisomy Syndrome Patau Chromosome 13 Trisomy Abnormal Autosomes 13
Malignant Gastric Germ Cell Tumor	Germ Cell Tumor Of The Stomach Germ Cell Tumour Of The Stomach Malignant Gastric Germ Cell Tumour
Malignant Gastric Teratoma	Malignant Teratoma Of Stomach Immature Gastric Teratoma
Angiomyolipoma	Angiomyolipoma Of Kidney
Cholangiocarcinoma	Cholangiocarcinoma, Susceptibility To Extrahepatic Cholangiocarcinoma Intrahepatic Cholangiocarcinoma Chlc Chlc, Susceptibility To Cc Cholangiocarcinoma Of Biliary Tract Cholangiocellular Carcinoma Distal Cholangiocarcinoma Perihilar Cholangiocarcinoma Bile Duct Cancer Cca Adult Primary Cholangiocellular Carcinoma Bile Duct Carcinoma
Liver Benign Neoplasm	Epithelial Hepatic And Intrahepatic Bile Duct Neoplasm
Germ Cell And Embryonal Cancer	Germ Cell And Embryonal Neoplasm
Gastric Adenocarcinoma	Adenocarcinoma Of Stomach Stomach Adenocarcinoma Adenocarcinoma Gastric Intestinal Type Adenocarcinoma Of Unspecified Site Diffuse Type Adenocarcinoma Of Unspecified Site
Immature Teratoma Of Ovary	Malignant Teratoma Of Ovary Ovarian Immature Teratoma Ovarian Malignant Teratoma Teratoma With Malignant Transformation Of Ovary
Apraxia	Apraxias Dyspraxia
Sarcomatous Intrahepatic Cholangiocarcinoma	Sarcomatoid Intrahepatic Cholangiocarcinoma
Mature Teratoma Of The Ovary
Testicular Disease	Testicular Dysfunction Testicular Diseases Disorder Of Testis Testis Disorder Testicular Disorders
Ovarian Germ Cell Teratoma	Germ Cell Teratoma Of Ovary Ovarian Teratoma
Pineal Dysgerminoma
Central Nervous System Mature Teratoma	Mature Teratoma Of The Cns
Mediastinum Seminoma	Seminoma Of Mediastinum
Ovarian Fetiform Teratoma
Giant Hemangioma
Beckwith-Wiedemann Syndrome	Wiedemann-Beckwith Syndrome BWS Exomphalos-Macroglossia-Gigantism Syndrome Emg Syndrome Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation Emg Abnormality Wbs Exomphalos Macroglossia Gigantism Syndrome Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation Macroglossia Exomphalos Gigantism
Pre-Eclampsia	Preeclampsia Gestational Hypertension Hypertension Induced By Pregnancy Pre-Eclamptic Toxaemia Pregnancy Associated Hypertension Proteinuric Hypertension Of Pregnancy Hypertension, Pregnancy-Induced, Susceptibility To Preeclampsia/Eclampsia Pregnancy Toxemia Toxaemia Of Pregnancy Gestational Proteinuric Hypertension Pregnancy-Induced Hypertension Toxemia Of Pregnancy Preeclampsia, Susceptibility To Transient Hypertension Of Pregnancy Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria Gestational Hypertension Nos Mild Proteinuric Hypertension Of Pregnancy Pih - [Pregnancy-Induced Hypertension] Pregnancy-Induced Hypertension Nos Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria Pe - [Pre-Eclampsia] Pre-Eclampsia Nos Pre-Eclamptic Nos Pregnancy Pre-Eclampsia Puerperal Pre-Eclampsia Pre-Eclampsia Toxaemia Toxaemia In Pregnancy Pet - [Pre-Eclamptic Toxaemia] Maternal Toxaemia
Tuberculous Epididymitis	Tuberculosis Of Epididymis
Intrahepatic Bile Duct Adenoma	Adenoma Of Intrahepatic Bile Duct Adenoma Of The Intrahepatic Bile Duct
Ovarian Gonadoblastoma
Testicular Infarct	Infarction Of Testis Testicular Infarction
Testicular Granulosa Cell Tumor	Granulosa Cell Tumor Of Testis Granulosa Cell Tumour Of Testis Testicular Granulosa Cell Tumour
Corpus Luteum Cyst	Cystic Corpus Luteum Luteal Cystic Ovary Disease Lutein Cyst Granulosa Lutein Cyst
Intrahepatic Cholestasis	Cholestasis, Intrahepatic Neonatal Intrahepatic Cholestasis Cholestasis Intrahepatic Cholestasis Of Pregnancy
Non-Gestational Choriocarcinoma	Choriocarcinoma, Non-Gestational
Juvenile Type Testicular Granulosa Cell Tumor	Juvenile Granulosa Cell Tumor Juvenile Granulosa Cell Tumour Juvenile Type Granulosa Cell Neoplasm Juvenile Type Granulosa Cell Tumor Juvenile Type Granulosa Cell Tumour Juvenile Type Testicular Granulosa Cell Tumour
Hepatic Infarction	Infarct Of Liver Hepatic Infarct Liver Infarct Liver Infarction
Diabetes Insipidus
Hepatic Coma	Hepatic Encephalopathy Hepatocerebral Intoxication
Klatskin'S Tumor	Klatskin Tumor Hilar Cholangiocarcinoma Perihilar Cholangiocarcinoma Hilar Cholangiocellular Carcinoma Klatskin Tumour Klatskin'S Tumour Perihilar Extrahepatic Bile Duct Carcinoma Hilar Cca Adenocarcinoma Of Hepatic Duct Klatskin Tumour Of Biliary Tree
Epididymis Disease
Fallopian Tube Adenofibroma
Glossopharyngeal Nerve Paralysis
Polyhydramnios
Choriocarcinoma Of Ovary	Ovarian Choriocarcinoma
Neuroendocrine Carcinoma	Neuroendocrine Cancer Carcinoma Neuroendocrine Carcinoma, Neuroendocrine
Blastoma	Embryoma
Epididymal Neoplasm	Neoplasm Of Epididymis
Liver Leiomyosarcoma	Leiomyosarcoma Of The Liver
Cholangiolocellular Carcinoma
Glycogen Storage Disease	Glycogenosis Glycogenoses Gsd Storage Disease, Glycogen Gsd - [Glycogen Storage Disease] Glycogen Thesaurismosis Diffuse Glycogenosis Generalised Glycogen Storage Disease Generalised Glycogenosis Generalised Glycogen Storage Disease Of Infants Glycogen Synthase Deficiency
Opisthorchiasis	Infection By Opisthorchis Infection Due To Opisthorchis Infection Due To Cat Liver Fluke Infection By Cat Liver Fluke Opisthorchiosis Cat Liver Fluke Fever Cat Liver Fluke Disease Opisthorchis Infestation Cat Liver Fluke Infestation
Mucinous Ovarian Cystadenoma	Mucinous Cystadenoma Of Ovary Ovarian Mucinous Cystadenoma
Anal Fistula	Anorectal Fistula Rectal Fistula Allingham Ulcer Perianal Fistula Fistula In Ano Anorectum Fistula
Chromosomal Duplication Syndrome
Rete Testis Adenocarcinoma	Adenocarcinoma Of Rete Testis Adenocarcinoma Of The Rete Testis
Rete Testis Neoplasm
Hepatic Tuberculosis	Tuberculosis, Hepatic Tuberculosis Of Liver Tuberculosis Hepatic
Intrahepatic Cholangiocarcinoma	Cholangiocarcinoma Intrahepatic Bile Duct Carcinoma Peripheral Cholangiocarcinoma Peripheral Intrahepatic Cholangiocarcinoma Adenocarcinoma Of Intra-Hepatic Bile Ducts Cholangiocarcinoma, Unspecified Site Cholangiocarcinoma Of Liver
Meningocele	Isolated Spina Bifida Spina Bifida Cleft Spine Open Spine Rachischisis Spinal Dysraphism Spinal Meningocele Congenital Meningocele
Pineal Region Germinoma	Pineal Germinoma
Peliosis Hepatis	Hepatic Peliosis Telangiectasis Of Liver Angiomatosis Of Liver Ph - [Peliosis Hepatis] Hepatic Angiomatosis
Childhood Endodermal Sinus Tumor	Childhood Endodermal Sinus Neoplasm Childhood Endodermal Sinus Tumour Paediatric Yolk Sac Tumour Pediatric Yolk Sac Tumor Childhood Yolk Sac Tumor
Granulomatous Orchitis	Non-Specific Granulomatous Orchitis
Pancreatic Acinar Cell Adenocarcinoma	Pancreatic Acinar Cell Carcinoma Acinar Cell Adenocarcinoma Of The Pancreas
Pineal Gland Cancer	Tumor Of The Pineal Region Malignant Pineal Region Tumor Malignant Tumor Of Pineal Gland Neoplasm Of Pineal Gland Neoplasm Of The Pineal Region Pineal Body Neoplasm Pineocytic Tumor Malignant Neoplasm Of Pineal Gland Pineal Gland Neoplasm Pineocytoma
Rectum Signet Ring Adenocarcinoma	Signet Ring Cell Adenocarcinoma Of Rectum
Non-Gestational Ovarian Choriocarcinoma
Cavernous Hemangioma	Hemangioma, Cavernous Cavernoma Cavernous Haemangioma
Obstructive Hydrocephalus
C Syndrome	Opitz Trigonocephaly Syndrome Trigonocephaly Trigonocephaly Syndrome Trigonocephaly C Syndrome Opitz C Trigonocephaly Opitz Trigonocephaly C Syndrome Otcs CSYN
Central Nervous System Germ Cell Tumor	Central Nervous System Germ Cell Tumour Germ Cell Tumor Of The Cns Germ Cell Tumour Of The Cns
Spermatocele
Botryoid Rhabdomyosarcoma	Sarcoma Botryoides Botryoid Sarcoma Botryoid-Type Embryonal Rhabdomyosarcoma
Liver Leiomyoma	Leiomyoma Of The Liver
Tethered Spinal Cord Syndrome	Spinal Dysraphism Tethered Cord Syndrome Occult Spinal Dysraphism Occult Spinal Dysraphism Sequence Segmental Vertebral Anomalies Tethered Spinal Cord Disease Tethered Cord Spina Bifida Occulta Cryptomerorachischisis Spina Bifida Occulta With Tethered Spinal Cord Sbo - [Spina Bifida Occulta]
Congenital Hypothyroidism	Cretinism Neonatal Hypothyroidism Ch Cht Congenital Myxedema Myxedema, Congenital Endemic Cretinism Congenital Iodine-Deficiency Syndrome Fetal Iodine Deficiency Syndrome Congenital Iodine-Deficiency Hypothyroidism Nos
Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 2	Aoa2 Ataxia With Oculomotor Apraxia Type 2 Scar1 SCAN2 Ataxia-Oculomotor Apraxia 2 Ataxia-Ocular Apraxia 2 Ataxia-Oculomotor Apraxia Type 2 Scan 2 Spinocerebellar Ataxia With Axonal Neuropathy Type 2 Spinocerebellar Ataxia, Autosomal Recessive 1, Formerly Scar1, Formerly Autosomal Recessive Spinocerebellar Ataxia-1 Spinocerebellar Ataxia, Autosomal Recessive, 1 Ataxia-Ocular Apraxia-2 Spinocerebellar Ataxia, Autosomal Recessive 1
Testicular Germ Cell Cancer	Germ Cell Tumor Of Testis Testicular Germ Cell Tumor Testicular Germ Cell Neoplasm Testicular Malignant Germ Cell Tumor
Malignant Adenofibroma	Adenocarcinofibroma
Childhood Ovarian Germ Cell Tumor	Pediatric Ovarian Germ Cell Tumor Paediatric Ovarian Germ Cell Neoplasm Paediatric Ovarian Germ Cell Tumour Pediatric Ovarian Germ Cell Neoplasm
Sex Cord-Gonadal Stromal Tumor	Sex Cord-Gonadal Stromal Tumour Sex Cord Stromal Tumour Sex Cord-Stromal Neoplasm Specialized Gonadal Neoplasm Specialized Gonadal Tumor Specialized Gonadal Tumour Sex Cord-Gonadal Stromal Tumors Sex Cord-Stromal Tumor Malignant Testicular Sex Cord-Stromal Tumor Sex Cord Stromal Tumor Of Testis
Obstructive Jaundice	Jaundice, Obstructive Cholestatic Jaundice Cholestatic Jaundice Syndrome Obstructive Hyperbilirubinemia Jaundice Obstructive Jaundice Cholestatic
Colonic Lymphangioma	Lymphangioma Of Colon Colon Lymphangioma
Malignant Mesenchymoma	Malignant Mesenchymal Tumor Mesenchymoma, Malignant Sarcoma Rat Malignant Renal Mesenchymal Tumor
Childhood Hepatocellular Carcinoma	Pediatric Hepatocellular Carcinoma Childhood Carcinoma Of Liver Cell Childhood Hepatoma Childhood Liver Cell Carcinoma Pediatric Carcinoma Of Liver Cell Pediatric Hepatoma Pediatric Liver Cell Carcinoma Childhood-Onset Hcc Childhood-Onset Hepatocellular Carcinoma Pediatric Hcc Childhood Liver Cancer
Tuberculous Peritonitis	Peritonitis, Tuberculous Peritonitis Tuberculous
Krukenberg Carcinoma	Krukenberg Tumor Krukenberg Neoplasm Krukenberg'S Tumor
Ovarian Cystadenoma	Cystoma Serosum Simplex Simple Cystoma Of Ovary Simple Cystoma Of The Ovary
Infected Hydrocele	Pyocele
Abdominal Tuberculosis
Hemochromatosis, Type 1	Hemochromatosis Hemochromatosis Type 1 Hereditary Hemochromatosis Hh HFE1 Hfe Hemochromatosis, Modifier Of Symptomatic Form Of Classic Hemochromatosis Symptomatic Form Of Hemochromatosis Type 1 Symptomatic Form Of Hfe-Related Hereditary Hemochromatosis Haemochromatosis Iron Storage Disorder Bronze Diabetes Hereditary Haemochromatosis Hlah Hfe Hemochromatosis, Hereditary Diabetes Bronze Classic Hemochromatosis Hfe-Associated Hereditary Hemochromatosis Hemochromatosis Classic Bronzed Cirrhosis Familial Hemochromatosis Genetic Hemochromatosis Hc Pigmentary Cirrhosis Primary Hemochromatosis Troisier-Hanot-Chauffard Syndrome Von Recklenhausen-Applebaum Disease Hemochromatosis 1 Primary Hereditary Hemochromatosis Bronze Cirrhosis
Testicular Torsion	Spermatic Cord Torsion Torsion Of Testis Torsion Of Testicular Cord Torsion Of Testicle Torsion Of Spermatic Cord Torsion Of Spermatic Cord Nos
Spermatocytoma	Spermatocytic Seminoma
Renal Pelvis Adenocarcinoma	Adenocarcinoma Of Renal Pelvis Adenocarcinoma Of The Kidney Pelvis
Fallopian Tube Benign Neoplasm
Biliary Tract Benign Neoplasm	Extrahepatic Bile Duct Neoplasm Neoplasm Of Extrahepatic Bile Ducts Tumor Of The Extrahepatic Bile Duct
Duodenal Atresia	Duodenal Stenosis Familial Duodenal Atresia
Bile Duct Adenoma	Cholangioadenoma Adenoma Bile Duct Adenoma, Bile Duct
Gestational Ovarian Choriocarcinoma
Ovarian Large-Cell Neuroendocrine Carcinoma	Non-Small-Cell Type Neuroendocrine Carcinoma Of Ovary Ovarian Large Cell Neuroendocrine Carcinoma
Gastrointestinal Tuberculosis	Tuberculosis Of Intestines, Peritoneum And Mesenteric Glands Tuberculosis, Gastrointestinal Tuberculosis Of Gastrointestinal Tract Tuberculosis Of Intestines, Peritoneum, And Mesenteric Glands
Testicular Fibroma
Childhood Germ Cell Cancer	Pediatric Germ Cell Tumor Paediatric Germ Cell Cancer Paediatric Germ Cell Neoplasm Pediatric Germ Cell Cancer Pediatric Germ Cell Neoplasm
Cystadenofibroma
Drug-Induced Hepatitis	Drug-Induced Chronic Hepatitis Chemical And Drug Induced Liver Injury, Chronic Hepatitis, Drug-Induced Hepatitis, Chronic, Drug-Induced
Bile Duct Disease	Bile Duct Diseases Bile Duct Disorder Disorder Of Bile Duct
Bile Duct Adenocarcinoma
Epididymis Cancer	Malignant Tumor Of Epididymis Malignant Epididymal Tumor Malignant Neoplasm Of Epididymis Neoplasm Of Epididymis
Ovarian Mucinous Cystadenocarcinoma	Mucinous Cystadenocarcinoma Of Ovary
Hypersplenism	Hypersplenia Big Spleen Syndrome Hyperfunction Of Spleen Increased Splenic Activity Spleen Metaplasia Splenic Metaplasia
Hepatorenal Syndrome	Hepato-Renal Syndrome Hepatorenal Failure Hrf - [Hepatorenal Failure] Hepatorenal Degeneration Hepatic Renal Syndrome Hepatic Renal Failure Renal Hepatic Failure Urohepatic Syndrome
Portal Hypertension	Hypertension, Portal Hypertension Portal Pht - [Portal Hypertension] Portal Htn
Mucinous Cystadenocarcinoma	Cystadenocarcinoma, Mucinous Pseudomucinous Cystadenocarcinoma Cystadenocarcinoma Mucinous
Febrile Seizures, Familial, 10	FEB10 Familial Febrile Seizures 10 Convulsions, Familial Febrile, 10 Familial Febrile Convulsions 10 Febrile Convulsions, Familial, 10
Biliary Tract Disease	Biliary Tract Diseases Biliary Tract Abnormality
Common Bile Duct Disease	Common Bile Duct Diseases
Pineal Region Meningioma	Pineal Meningioma
Gonadoblastoma	GBY
Cardiovascular Organ Benign Neoplasm
Hypothyroidism	Thyroid Diseases Thyroid Disease Thyroid Deficiency Thyroid Insufficiency Dysfunction Thyroid Thyroid Dysfunction
Placental Abruption	Abruptio Placentae Abruptio Placenta Abortion, Threatened Threatened Miscarriage Haemorrhage Specified As Due To Threatened Abortion Spontaneous Threatened Abortion
Intrahepatic Biliary Papillomatosis	Intrahepatic Bile Duct Papillary Neoplasm
Telangiectasis	Telangiectasia
Testicular Gonadoblastoma
Mixed Cell Type Cancer	Malignant Mixed Neoplasm Malignant Mixed Tumor Mixed Neoplasm Mixed Tumor, Malignant Malignant Mixed Cancer Mixed Tumor Malignant Mixed Tumor, Not Otherwise Specified Mixed Salivary Gland Tumor Mixed Tumor, Not Otherwise Specified
Adult Hepatocellular Carcinoma	Adult Primary Hepatocellular Carcinoma Adult Hepatoma Adult Hcc
Intratubular Embryonal Carcinoma	Stage 0 Testicular Embryonal Carcinoma
Inguinal Hernia	Hernia Inguinal Hernia, Inguinal Inguinal Hernias Bubonocele Indirect Inguinal Hernia Direct Inguinal Hernia Oblique Inguinal Hernia Scrotal Hernia Ih - [Inguinal Hernia]
Cholecystolithiasis
Budd-Chiari Syndrome	Hepatic Vein Thrombosis Chiari Syndrome BDCHS Membranous Obstruction Of The Inferior Vena Cava Budd-Chiari Syndrome, Somatic Movc Budd-Chiari Syndrome, Susceptibility To, Somatic Budd-Chiari Syndrome, Susceptibility To Membranous Obstruction Of Inferior Vena Cava Hepatic Vein Block Obstruction Of Hepatic Veins Hepatic Vein Obstruction Hepatic Venous Block
Infiltrating Angiolipoma	Angiolipoma, Infiltrating
Subserous Uterine Fibroid	Subserous Leiomyoma Of Uterus
Alcohol Use Disorder	Alcohol Abuse Alcoholism Ethanol Abuse Alcohol Addiction Alcohol Dependence Alcoholic Intoxication, Chronic Alcohol-Related Disorders
Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia	Aoa1 Ataxia-Telangiectasia-Like Disorder EAOH Eoca-Ha Ataxia With Oculomotor Apraxia Type 1 Ataxia-Oculomotor Apraxia 1 Ataxia-Oculomotor Apraxia Syndrome AOA Ataxia-Telangiectasia-Like Syndrome Ataxia-Oculomotor Apraxia Type 1 Ataxia With Oculomotor Apraxia Cerebellar Ataxia, Early-Onset, With Hypoalbuminemia Early-Onset Ataxia With Oculomotor Apraxia And Hypoalbuminemia Early-Onset Cerebellar Ataxia With Hypoalbuminemia Adult Onset Ataxia With Oculomotor Apraxia Early-Onset Ataxia With Ocular Motor Apraxia And Hypoalbuminemia Scan2 Scar1 Spinocerebellar Ataxia With Axonal Neuropathy Type 2 Spinocerebellar Ataxia, Recessive, Non-Friedreich Type 1 Atld Ataxia Early-Onset With Oculomotor Apraxia And Hypoalbuminemia Cerebellar Ataxia Early-Onset With Hypoalbuminemia Ataxia-Oculomotor Apraxia Spinocerebellar Ataxia, Autosomal Recessive 1
Epididymis Adenocarcinoma	Adenocarcinoma Of The Epididymis
Endometrial Small Cell Carcinoma
Esophagus Lymphoma	Lymphoma Of Esophagus Lymphoma Of Oesophagus Oesophagus Lymphoma Esophageal Lymphoma
Non-Alcoholic Steatohepatitis	Nonalcoholic Steatohepatitis Nash Nash - [Non-Alcoholic Steatohepatitis] Non-Alcoholic Steatohepatosis
Intestinal Atresia
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Trophoblastic Neoplasm	Trophoblastic Tumor Trophoblastic Neoplasms
Microinvasive Gastric Cancer	Early Gastric Cancer Surface Gastric Cancer
Embryonal Testis Carcinoma	Testicular Embryonal Carcinoma Embryonal Carcinoma Of Testis Embryonal Carcinoma Of The Testis
Lipomatosis, Multiple	Lipoma Familial Multiple Lipomatosis Lipomatosis, Familial Multiple Benign Lipomatous Tumor Lipomatous Neoplasm Multiple Lipomatosis Fml Lipo Benign Tumor Of Adipose Tissue Lipomatous Tumor Tumor Of Adipose Tissue Neoplasms, Adipose Tissue Lipomas
Sclerosing Cholangitis	Fibrosing Cholangitis Cholangitis, Sclerosing Primary Sclerosing Cholangitis
Rectum Neuroendocrine Neoplasm	Neuroendocrine Tumor Of Rectum Neuroendocrine Tumor Of The Rectum Net Of The Rectum Rectal Net Rectal Neuroendocrine Tumor Rectal Neuroendocrine Neoplasm
Metal Metabolism Disorder	Metal Metabolism, Inborn Errors Inborn Metal Metabolism Disorder
Pancreas Sarcoma	Sarcoma Of Pancreas
Ichthyosis	Ichthyoses Non-Syndromic Ichthyosis Congenital Ichthyosis
Gestational Trophoblastic Neoplasm	Hydatidiform Mole Molar Pregnancy Gestational Trophoblastic Neoplasia Gestational Trophoblastic Tumor Gtn Gestational Trophoblastic Disease Gestational Trophoblastic Neoplasms Hydatidiform Mole, Recurrent, 1 Hydatidiform Mole Benign Trophoblastic Disease Trophoblastic Disease Nos Trophoblastic Disorder Vesicular Mole Nos Vesicular Mole Hydatidiform Mole Nos
Cecal Disease	Cecal Diseases Disorder Of Cecum
Bilirubin Metabolic Disorder	Hyperbilirubinemia Hereditary Hyperbilirubinemia Hyperbilirubinemia, Hereditary Hyperbilirubinaemia
Gestational Choriocarcinoma	Gestational Chorionepithelioma Molar Pregnancy With Choriocarcinoma
Biliary Tract Cancer	Malignant Tumour Of Biliary Tract Biliary Tract Neoplasms Biliary Tract Neoplasm
Substance Abuse	Substance-Related Disorders Substance Abuse Problem
Autosomal Recessive Cerebellar Ataxia	Arca
Reproductive Organ Benign Neoplasm
Adult Type Testicular Granulosa Cell Tumor
Cryptorchidism, Unilateral Or Bilateral	Cryptorchidism Undescended Testicle Undescended Testis Cryptorchism Undescended Testicles CRYPTO Impaired Testicular Descent Cryptosporidiosis Retained Testis Unilateral Cryptorchidism Unilateral Undescended Testis Nondescent Unilateral Testicle Unilateral Cryptorchism Ectopic Testis, Unilateral Bilateral Cryptorchidism Bilateral Cryptorchism Bilateral Nondescent Testicle Bilateral Undescended Testes Bilateral Ectopic Testes
Galloway-Mowat Syndrome 1	Galloway Syndrome Nephrosis-Neuronal Dysmigration Syndrome Nephrosis-Microcephaly Syndrome Camos Scar5 GAMOS1 Microcephaly, Hiatal Hernia, And Nephrotic Syndrome Microcephaly, Hiatal Hernia And Nephrotic Syndrome Cerebellar Ataxia With Mental Retardation, Optic Atrophy, And Skin Abnormalities Spinocerebellar Ataxia, Autosomal Recessive 5, Formerly Scar5, Formerly Spinocerebellar Ataxia Autosomal Recessive 5 Cerebellar Ataxia With Intellectual Disability Optic Atrophy And Skin Abnormalities Camos Syndrome Cerebellar Ataxia-Intellectual Disability-Optic Atrophy-Skin Abnormalities Syndrome Galloway-Mowat Syndrome Spinocerebellar Ataxia, Autosomal Recessive, 5 Galloway Mowat Syndrome Spinocerebellar Ataxia, Autosomal Recessive 5
Disorder Of Sexual Development	Disorder Of Sex Development Disorders Of Sex Development Sex Development Disorder Sex Differentiation Disease Dsd Sex Differentiation Disorders
Cholangitis, Primary Sclerosing	Primary Sclerosing Cholangitis PSC Sclerosing Cholangitis Cholangitis, Sclerosing Cholangitis Primary Sclerosing Psc - [Primary Sclerosing Cholangitis]
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Gallbladder Disease	Gallbladder Diseases Gall Bladder Gall Bladder Diseases Abnormal Gallbladder Function
Physical Disorder	Physical Illness
Gummatous Syphilis
Lymphangioma	Lymphatic Malformation Lymphatic Malformations Benign Lymphangioma Congenital Lymphangioma Lymphangiomas
Crigler-Najjar Syndrome, Type I	Crigler-Najjar Syndrome Crigler-Najjar Syndrome Type 1 Bilirubin Udp Glucuronyl Transferase Deficiency Crigler Najjar Syndrome Crigler Najjar Syndrome, Type 1 Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency Bilirubin-Ugt Deficiency Hyperbilirubinemia, Crigler-Najjar Type I Hblrcn1 Familial Nonhemolytic Unconjugated Hyperbilirubinemia Hereditary Unconjugated Hyperbilirubinemia Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency Type 1 Bilirubin-Ugt Deficiency Type 1 Crigler-Najjar Syndrome 1 CN1 Cn-I Crigler-Najjar Syndrome Type I Hereditary Unconjugated Hyperbilirubinaemia Ugt Deficiency Bilirubin Glucuronosyltransferase Deficiency Crigler-Najjar Disease Or Syndrome Deficiency Of Glucuronosyltransferase Glucuronyl Transferase Deficiency Glucuronyltransferase Deficiency Udp Glucuronyl Transferase Deficiency Cns - [Crigler-Najjar Syndrome] Congenital Familial Nonhemolytic Jaundice
Diabetes Mellitus	Diabetes
Primary Biliary Cholangitis	Primary Biliary Cirrhosis Biliary Liver Cirrhosis Chronic Nonsuppurative Destructive Cholangitis Familial Primary Biliary Cirrhosis Pbc Hanot Syndrome Cholestatic Cirrhosis Biliary Cirrhosis Primary Liver Cirrhosis, Biliary Hanot'S Cirrhosis Biliary Cirrhosis Pericholangiolic Biliary Cirrhosis Tannhauser-Magendantz Syndrome Hanot-Rossle Syndrome Hypertrophic Cirrhosis Todd Cirrhosis Hanot Cirrhosis Charcot Cirrhosis Mahon-Tannhauser Syndrome Toxic Cirrhosis Hypertrophic Biliary Cirrhosis Monolobular Cirrhosis Unilobar Cirrhosis Xanthomatous Biliary Cirrhosis
Wilms Tumor 1	Nephroblastoma Wilms Tumor WT1 Wilms' Tumor Bilateral Wilms Tumor Wilms Tumor, Type 1 Wilms Tumor, Somatic Adult Nephroblastoma Wt1 Disorder Renal Embryonic Tumor Adult Kidney Wilms Tumor Childhood Kidney Wilms Tumor Nonanaplastic Kidney Wilms Tumor
Congenital Nervous System Abnormality	Congenital Neurologic Anomaly Congenital Nervous System Disorder
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0600	Tafluprost	Control	99.69%	Yes
HY-B0601	Tafluprost acid		99.97%	Unkown
HY-116733	Tafluprost ethyl ester	Agonist	/	Unkown

Clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Phase
HY-16031B	AFP464 dihydrochloride	99.45%	Phase 2
HY-16031	AFP464 free base	/	Phase 2
HY-16031A	AFP464	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (16)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-103469	Peroxy Orange 1		99.20%	Unkown
HY-175606	EVT0185	Inhibitor	99.39%	Unkown
HY-160042	AFP aptamer sodium		94.04%	Unkown
HY-105315	AFP-07	Agonist	/	Unkown
HY-129293	AFP-07 free acid	Agonist	/	Unkown
HY-187304S	[U-15N]-AFP		/	Unkown
HY-187307S	[U-15N]-PIVKA-II		/	Unkown
HY-NP228	Alpha fetoprotein, human		/	Unkown
HY-RS00435	AFP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS15031	TRIM26 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-129922	16(R)-AFP 07 free acid		/	Unkown
HY-160042A	AFP aptamer sodium scrambled negative control		/	Unkown
HY-160042B	FAM labled AFP aptamer sodium		/	Unkown
HY-160042C	Cy3 labled AFP aptamer sodium		/	Unkown
HY-RS16874	Afp Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23316	Afp Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991858	Anti-AFP Antibody		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	AFP	RGD	RGD:2065
Bos taurus	AFP	VGNC	VGNC:25717
Canis familiaris	AFP	VGNC	VGNC:37692
Felis catus	AFP	VGNC	VGNC:59671
Macaca mulatta	AFP	VGNC	VGNC:69741
Mus musculus	AFP	MGD	MGI:87951
Others	AFP	NCBI