Mos - Moloney sarcoma oncogene Gene
Also Known as c-mos
Species: Mus musculus
Summary
Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including microtubule Cytoskeleton organization; negative regulation of metaphase/anaphase transition of meiotic cell cycle; and positive regulation of MAPK cascade. Acts upstream of or within regulation of meiotic nuclear division. Located in cytoplasm. Is expressed in brain; early conceptus; gonad; large intestine; and metanephros. Orthologous to human MOS (MOS proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]
Mos Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_020021.3 | NP_064405.2 | proto-oncogene serine/threonine-protein kinase mos |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in chromatin organization |
IMP
IMP: Inferred from mutant phenotype
|
8631259 | MGI |
| involved in establishment of meiotic spindle orientation |
IMP
IMP: Inferred from mutant phenotype
|
8692939 | MGI |
| involved in meiotic spindle organization |
IMP
IMP: Inferred from mutant phenotype
|
8631259 | MGI |
| involved in negative regulation of metaphase/anaphase transition of meiotic cell cycle |
IMP
IMP: Inferred from mutant phenotype
|
8015609 | MGI |
| involved in positive regulation of MAPK cascade |
IMP
IMP: Inferred from mutant phenotype
|
8631259 | MGI |
| acts upstream of or within regulation of meiotic nuclear division |
IGI
IGI: Inferred from genetic interaction
|
20724447 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
12207927 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
proto-oncogene serine/threonine-protein kinase mos |
|
|