Mos - Moloney sarcoma oncogene Gene

Also Known as c-mos

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17451

Summary

Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including microtubule Cytoskeleton organization; negative regulation of metaphase/anaphase transition of meiotic cell cycle; and positive regulation of MAPK cascade. Acts upstream of or within regulation of meiotic nuclear division. Located in cytoplasm. Is expressed in brain; early conceptus; gonad; large intestine; and metanephros. Orthologous to human MOS (MOS proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mos Products (1)

mRNA Protein Name
NM_020021.3 NP_064405.2 proto-oncogene serine/threonine-protein kinase mos
Biological Process GO Annotation Evidence References Source
involved in chromatin organization IMP
IMP: Inferred from mutant phenotype
8631259 MGI
involved in establishment of meiotic spindle orientation IMP
IMP: Inferred from mutant phenotype
8692939 MGI
involved in meiotic spindle organization IMP
IMP: Inferred from mutant phenotype
8631259 MGI
involved in negative regulation of metaphase/anaphase transition of meiotic cell cycle IMP
IMP: Inferred from mutant phenotype
8015609 MGI
involved in positive regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
8631259 MGI
acts upstream of or within regulation of meiotic nuclear division IGI
IGI: Inferred from genetic interaction
20724447 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12207927 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proto-oncogene serine/threonine-protein kinase mos

  • c-mos proto-oncogene

  • oocyte maturation factor mos

  • proto-oncogene c-Mos

Orthologs Information

Species Symbol Source ID
Homo sapiens Mos NCBI NCBI:4342