2. Gene
  3. Prkce - protein kinase C, epsilon Gene

Prkce - protein kinase C, epsilon Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pkce; PKC[e]; PKCepsilon; 5830406C15Rik

Gene ID: 18754 | Gene type: protein coding

About Prkce

Chromosome 17: 86,475,213-86,965,347 forward strand.GRCm39:CM001010.3

This gene has 5 transcripts (splice variants), 312 orthologues, 9 paralogues and is associated with 15 phenotypes. Broad expression in frontal lobe adult (RPKM 22.3), cortex adult (RPKM 2.6) and 19 other tissues.

Summary

Enables several functions, including 14-3-3 protein binding activity; actin monomer binding activity; and calcium-independent protein kinase C activity. Involved in several processes, including TRAM-dependent Toll-like Receptor 4 signaling pathway; positive regulation of actin filament polymerization; and positive regulation of fibroblast migration. Acts upstream of or within several processes, including cellular response to alcohol; positive regulation of cell communication; and regulation of secretion. Located in several cellular components, including cytosol; mitochondrion; and perinuclear region of cytoplasm. Colocalizes with Golgi apparatus. Is expressed in several structures, including central nervous system; genitourinary system; heart ventricle; neural retina; and salivary gland. Orthologous to human PRKCE (protein kinase C epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Prkce Products(1)

mRNA Protein Name
NM_011104.3 NP_035234.1 protein kinase C epsilon type

Prkce Protein Structure

C2_PKC_epsilon

C2_PKC_epsilon: cd04014 (2 - 134)

C1_nPKC_epsilon-like_rpt1

C1_nPKC_epsilon-like_rpt1: cd20835 (160 - 223)

C1_nPKC_epsilon-like_rpt2

C1_nPKC_epsilon-like_rpt2: cd20838 (240 - 294)

STKc_nPKC_epsilon

STKc_nPKC_epsilon: cd05591 (411 - 731)

  • 0
  • 200
  • 400
  • 600
  • 737 a.a.
Protein Preferred Names Protein Names

protein kinase C epsilon type

PCK epsilon

nPKC-epsilon

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11125 PRKCE Human Pre-designed siRNA Set A / Unkown
HY-RS11126 Prkce Mouse Pre-designed siRNA Set A / Unkown
HY-RS11127 Prkce Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkce NCBI NCBI:5581