Rbl2 - RB transcriptional corepressor like 2 Gene

Also Known as Rb2; PRB2; p130; RBR-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19651

Summary

Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and promoter-specific chromatin binding activity. Predicted to be involved in cell differentiation; negative regulation of G1/S transition of mitotic cell cycle; and regulation of lipid kinase activity. Predicted to act upstream of or within negative regulation of gene expression. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and retina. Orthologous to human RBL2 (RB transcriptional corepressor like 2). [provided by Alliance of Genome Resources, Apr 2022]

Rbl2 Products (3)

mRNA Protein Name
NM_001282000.1 NP_001268929.1 retinoblastoma-like protein 2 isoform 2
NM_001282001.1 NP_001268930.1 retinoblastoma-like protein 2 isoform 3
NM_011250.4 NP_035380.3 retinoblastoma-like protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11571651 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
10082561 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
10082561 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinoblastoma-like protein 2

  • 130 kDa retinoblastoma-associated protein

  • retinoblastoma-like 2

  • retinoblastoma-related protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N2252 Licarin A Inhibitor 99.83% Unkown
HY-P1640 (Trp63,Trp64)​-​C3a(63-77) Agonist 99.23% Unkown
HY-116295 MRS2690 / Unkown
HY-116295A MRS2690 disodium / Unkown
HY-139247 pNPS-DHA / Unkown
HY-N15708 Dichotomine C Inhibitor / Unkown
HY-P11163 Eumenitin / Unkown
HY-RS11730 RBL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N12116 Maceneolignan A Inhibitor / Unkown
HY-RS21415 Rbl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27934 Rbl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbl2 NCBI NCBI:5934