Ccl8 - chemokine (C-C motif) ligand 8 Gene

Also Known as HC14; Mcp2; MCP-2; Scya8; 1810063B20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20307

Summary

Predicted to enable Chemokine Receptor binding activity; Phospholipase activator activity; and protein kinase activity. Acts upstream of or within positive regulation of myoblast differentiation and positive regulation of myoblast fusion. Located in extracellular space. Is expressed in ductus deferens; epididymis; esophagus; heart ventricle; and testis. Orthologous to human CCL8 (C-C motif chemokine ligand 8). [provided by Alliance of Genome Resources, Apr 2022]

Ccl8 Products (1)

mRNA Protein Name
NM_021443.3 NP_067418.1 C-C motif chemokine 8 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of myoblast differentiation IMP
IMP: Inferred from mutant phenotype
23844157 MGI
acts upstream of or within positive regulation of myoblast fusion IMP
IMP: Inferred from mutant phenotype
23844157 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
23460747 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-C motif chemokine 8

  • monocyte chemoattractant protein-2

  • monocyte chemotactic protein 2

  • small-inducible cytokine A8

Recombinant Ccl8 Proteins

Cat. No. Product Name Accession Purity
HY-P7239 MCP-2/CCL8 Protein, Mouse Q9Z121 (G24-P97) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P7771 MCP-2/CCL8 Protein, Mouse (HEK293, His) Q9Z121 (E20-P97) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-B0498 Bindarit Inhibitor 99.59% Phase 3
HY-165528 Histamine glutarimide Inhibitor / Phase 3

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16843 Ccl8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02107 CCL8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174749 Human CCL8 mRNA / Unkown
HY-185661 IBS007125 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccl8 NCBI NCBI:6355