Shc3 - src homology 2 domain-containing transforming protein C3 Gene

Also Known as Rai; ShcC; N-Shc

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20418

Summary

Predicted to enable phosphotyrosine residue binding activity and receptor tyrosine kinase binding activity. Acts upstream of or within glutamatergic synaptic transmission and learning or memory. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; liver and biliary system; musculoskeletal system; and reproductive system. Orthologous to human SHC3 (SHC adaptor protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Shc3 Products (1)

mRNA Protein Name
NM_009167.5 NP_033193.3 SHC-transforming protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11877420 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within learning or memory IMP
IMP: Inferred from mutant phenotype
15716419 MGI
acts upstream of or within synaptic transmission, glutamatergic IMP
IMP: Inferred from mutant phenotype
15716419 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SHC-transforming protein 3

  • SH2 domain protein C3

  • SHC-transforming protein C

  • neuronal Shc

Shc3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Shc3 Q61120 App Mus musculus P12023
CoIP
11877420
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12858 SHC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22323 Shc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shc3 NCBI NCBI:53358