Ncor2 - nuclear receptor co-repressor 2 Gene

Also Known as SMRT; N-CoR; SMRTe

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20602

Summary

Enables chromatin binding activity; sequence-specific DNA binding activity; and transcription corepressor activity. Acts upstream of or within several processes, including animal organ development; negative regulation of fat cell differentiation; and positive regulation of protein deacetylation. Located in nuclear body. Part of histone deacetylase complex. Is expressed in several structures, including branchial arch; central nervous system; limb; retina layer; and tooth. Used to study myelofibrosis. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human NCOR2 (nuclear receptor corepressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ncor2 Products (3)

mRNA Protein Name
NM_001253904.1 NP_001240833.1 nuclear receptor corepressor 2 isoform 2
NM_001253905.1 NP_001240834.1 nuclear receptor corepressor 2 isoform 3
NM_011424.3 NP_035554.3 nuclear receptor corepressor 2 isoform 1
Protein Preferred Names Protein Names

nuclear receptor corepressor 2

  • N-CoR2

  • T3 receptor-associating factor

  • TRAC

  • silencing mediator of retinoic acid and thyroid hormone receptor

  • silencing mediator of retinoid acid and thyroid hormone receptor

  • thyroid-, retinoic-acid-receptor-associated corepressor

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncor2 NCBI NCBI:9612