Sstr4 - somatostatin receptor 4 Gene

Also Known as sst4; Smstr4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20608

About Sstr4

Chromosome 2: 148,237,264-148,238,687 forward strand.GRCm39:CM000995.3

This gene has 1 transcript (splice variant), 100 orthologues, 15 paralogues and is associated with 12 phenotypes.

Summary

Predicted to enable neuropeptide binding activity and Somatostatin Receptor activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of arachidonic acid secretion; and regulation of signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in several structures, including brain; eye; genitourinary system; gut; and respiratory system. Orthologous to human SSTR4 (Somatostatin Receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Sstr4 Products (1)

mRNA Protein Name
NM_009219.3 NP_033245.2 somatostatin receptor type 4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
17950729 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Sstr4 Protein Structure

7tmA_SSTR4

7tmA_SSTR4: cd15973 (44 - 318)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (45 - 71)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (78 - 104)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (115 - 145)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (157 - 179)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (204 - 233)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (248 - 278)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (286 - 311)

  • 0
  • 100
  • 200
  • 300
  • 385 a.a.
Protein Preferred Names Protein Names

somatostatin receptor type 4

  • SS-4-R

  • SS4-R

  • SS4R

Sstr4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Sstr4 P49660 Dlg4 Mus musculus Q62108
Pull Down
17950729
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-105172 TT-232 Agonist 98.72% Phase 2
HY-P0024 Veldoreotide Activator / Phase 2
HY-P1384 L803 Agonist / Phase 2

Pre-clinical Phase

Bioactive Molecules (10)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P1932 Cortistatin-14 99.98% Unkown
HY-139347 Mazisotine Agonist 99.54% Unkown
HY-P0024A Veldoreotide TFA Agonist 98.97% Unkown
HY-P4452 PRL 2915 Antagonist 99.92% Unkown
HY-P3618 Cortistatin-29 (reduced) 98.12% Unkown
HY-P4469 PRL 3195 Antagonist / Unkown
HY-W1117589 SSTR4 agonist 6 Agonist / Unkown
HY-142701 SSTR4 agonist 4 Activator / Unkown
HY-P2150 Cortistatin-29 (rat) / Unkown
HY-172147 SSTR4 agonist 5 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sstr4 NCBI NCBI:6754